440103-83-3

Basic information

• Product Name: [3S,4S,5R,6R]-5-((trisopropylsilyl)oxy)-3-(4-methoxy-benzyloxy)-4,6-dimethyl-7-(triphenylmethyl)oxy-heptanal
• Synonyms: [3S,4S,5R,6R]-5-((trisopropylsilyl)oxy)-3-(4-methoxy-benzyloxy)-4,6-dimethyl-7-(triphenylmethyl)oxy-heptanal
• CAS NO: 440103-83-3
• Molecular Weight: 709.054
• Mol File: 440103-83-3.mol

Chemical Properties

• CAS DataBase Reference: [3S,4S,5R,6R]-5-((trisopropylsilyl)oxy)-3-(4-methoxy-benzyloxy)-4,6-dimethyl-7-(triphenylmethyl)oxy-heptanal(CAS DataBase Reference)
• NIST Chemistry Reference: [3S,4S,5R,6R]-5-((trisopropylsilyl)oxy)-3-(4-methoxy-benzyloxy)-4,6-dimethyl-7-(triphenylmethyl)oxy-heptanal(440103-83-3)
• EPA Substance Registry System: [3S,4S,5R,6R]-5-((trisopropylsilyl)oxy)-3-(4-methoxy-benzyloxy)-4,6-dimethyl-7-(triphenylmethyl)oxy-heptanal(440103-83-3)

Safety Data

• Hazardous Substances Data: 440103-83-3(Hazardous Substances Data)

Upstream product

• 440103-89-9 [3S,4S,5R,6R]-5-((triisopropylsilyl)oxy)-3-(4-methoxy-benzyloxy)-4,6-dimethyl-7-(triphenylmethyl)oxy-heptan-1-ol 
• 76-83-5 trityl chloride 
• 440103-87-7 [2R,3R,4S,5S]-3-((triisopropylsilyl)oxy)-5-(4-methoxy-benzyloxy)-2,4-dimethylheptane-1,7-diol 
• 440103-88-8 [2R,3R,4S,4(2S,4S)]-3-((triisopropylsilyl)oxy)-4-[2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-2-methyl-pentan-1-ol 

Downstream Products

• 440103-97-9 (2S,7S,8S,9R,10R)-4-Benzenesulfonyl-2-{(2R,5S)-5-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-5-methyl-tetrahydro-furan-2-yl}-7-(4-methoxy-benzyloxy)-8,10-dimethyl-9-triisopropylsilanyloxy-2-trimethylsilanyloxy-11-trityloxy-undecan-5-ol 
• 56092-81-0 ionomycin 
• 440104-03-0 benzoic acid 1-[2,5'-dimethyl-5'-(1-t-butyldimetylsilyloxy-ethyl)-octahydro-[2,2']bifuranyl-5-ylmethyl]-2,4-dimethyl-5-oxo-3-triisopropylsilyloxy-pentyl ester 
• 440104-24-5 [1S,1(2S,5S,2'R,5'S,5'(1R)),2S,3R,4R]-benzoic acid 1-[2,5'-dimethyl-5'-(1-t-butyldimethylsilyloxy-ethyl)-octahydro-[2,2']bifuranyl-5-ylmethyl]-5-hydroxy-2,4-dimethyl-3-triisopropylsilyloxy-pentyl ester 
• 1027419-70-0 Benzoic acid (E)-(1S,2S,3R,4R,8R,10R)-1-{(2S,5S,2'R,5'S)-5'-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-ylmethyl}-2,4,8,10-tetramethyl-11-oxo-3-triisopropylsilanyloxy-undec-5-enyl ester 
• 440104-05-2 [1S,1(2S,5S,2'R,5'S,5'(1R)),2S,3R,4R,5E,8R,10R]-benzoic acid 1-[5'-(1-t-butyldimethylsilyloxy-ethyl)-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-yl-methyl]-11-hydroxy-2,4,8,10-tetramethyl-3-triisopropylsilyloxy-undec-5-enyl ester 
• 440104-02-9 [1S,1(2S,5S,2'R,5'S,5'(1R)),2S,3R,4R]-benzoic acid 1-[2,5'-dimethyl-5'-(1-t-butyldimethylsilyloxy-ethyl)-octahydro-[2,2']bifuranyl-5-ylmethyl]-2,4-dimethyl-3-triisopropylsilyloxy-5-trityloxy-pentyl ester 
• 440104-00-7 [2S,2(2R,5S,5(1R)),7S,8S,9R,10R]-7-hydroxy-9-triisopropylsilyloxy-8,10-dimethyl-2-[5-methyl-5-(1-(t-butyldimethylsilyloxy)-ethyl)tetrahydrofuran-2-yl]-2-trimethylsilyloxy-11-trityloxy-undecan-5-one 
• 440104-25-6 benzoic acid 3-hydroxy-1-[5'-(1-hydroxy-ethyl)-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-yl-methyl]-20-methoxycarbonyl-2,4,8,10,14,16,18-heptamethyl-11,13-dioxo-eicos-5-enyl ester 
• 440104-04-1 [1S,1(2S,5S,2'R,5'S,5'(1R)),2S,3R,4R,5E,8R,10R]-benzoic acid 1-[5'-(1-t-butyldimethylsilyloxy-ethyl)-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-yl-methyl]-11-(4-methoxy-benzyloxy)-2,4,8,10-tetramethyl-3-triisopropylsilyloxy-undec-5-enyl ester 
• 440104-01-8 [2S,2(2R,5S,5(1R)),5R,7S,8S,9R,10R]-7-benzoyloxy-5-hydroxy-9-triisopropylsilyloxy-8,10-dimethyl-2-[5-methyl-5-(1-(t-butyldimethylsilyloxy)-ethyl)tetrahydrofuran-2-yl]-2-trimethylsilyloxy-11-trityloxy-undecane 
• 440103-99-1 [2S,2(2R,5S,5(1R)),7S,8S,9R,10R]-9-triisopropylsilyloxy-7-(4-methoxy-benzyloxy)-8,10-dimethyl-2-[5-methyl-5-(1-(t-butyldimethylsilyloxy)-ethyl)tetrahydrofuran-2-yl]-2-trimethylsilyloxy-11-trityloxy-undecan-5-one 
• 440103-98-0 (2S,7S,8S,9R,10R)-4-Benzenesulfonyl-2-{(2R,5S)-5-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-5-methyl-tetrahydro-furan-2-yl}-7-(4-methoxy-benzyloxy)-8,10-dimethyl-9-triisopropylsilanyloxy-2-trimethylsilanyloxy-11-trityloxy-undecan-5-one 
• 440104-06-3 [1S,1(2S,5S,2'R,5'S,5'(1R)),2S,3R,4R,5E,8R,10R,14S,16S,18S]-benzoic acid 1-[5'-(1-TBDMS-ethyl)-2,5'-dimethyl-octahydro[2,2']bifuranyl-5-yl-methyl]-20-methoxycarbonyl-2,4,8,10,14,16,18-heptamethyl-11,13-dioxo-3-triisopropylsilyloxy-eicos-5-enyl ester 

Relevant articles and documents

Total Synthesis of Ionomycin Using Ring-Opening Strategies

(Matrix Presented) The total synthesis of the polyether antibiotic ionomycin, a calcium ionophore, is described. The synthesis demonstrates the utility of ring-opening methodologies as applied to the synthesis of polypropionate and deoxypolypropionate subunits, which are found in two of the four fragments in the synthesis.