440103-90-2

Upstream product

• 2746-25-0 p-Methoxybenzyl bromide 
• 440104-08-5 (1R,2R,3R,4R,7R)-2,4,7-trimethyl-3-((t-butyldimethylsilyl)oxy)-cyclohept-5-enol 
• 824-94-2 p-methoxybenzyl chloride 
• 96691-93-9 (1R,2R,3r,4S,5S)-2,4-dimethyl-8-oxabicyclo[3.2.1]oct-6-en-3-ol 
• 37081-58-6 (1R,2S,4R,5S)-2,4-dimethyl-8-oxa-bicyclo[3.2.1]oct-6-en-3-one 
• 292631-99-3 (1R,2R,3R,4R,7R)-2,4,7-trimethyl-cyclohept-5-en-1,3-diol 

Downstream Products

• 440659-80-3 [2R,3R,4R,5R,6R]-2,4,6-trimethyl-5-(4-methoxybenzyloxy)-3-((t-butyldimethylsilyl)oxy)-heptane-1,7-diol 

Relevant academic research and scientific papers

Total Synthesis of Ionomycin Using Ring-Opening Strategies

(Matrix Presented) The total synthesis of the polyether antibiotic ionomycin, a calcium ionophore, is described. The synthesis demonstrates the utility of ring-opening methodologies as applied to the synthesis of polypropionate and deoxypolypropionate subunits, which are found in two of the four fragments in the synthesis.