440105-45-3 Usage
Chemical Properties
Brown Semi-solid
Uses
5-Acetyloxy-1,3-oxathiolane-2-carboxylic Acid is used in the preparation of Lamivudine.
Check Digit Verification of cas no
The CAS Registry Mumber 440105-45-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,0,1,0 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 440105-45:
(8*4)+(7*4)+(6*0)+(5*1)+(4*0)+(3*5)+(2*4)+(1*5)=93
93 % 10 = 3
So 440105-45-3 is a valid CAS Registry Number.
440105-45-3Relevant articles and documents
Practical enantioselective synthesis of lamivudine (3TC) via a dynamic kinetic resolution
Goodyear, Michael D.,Hill, Malcolm L.,West, Jono P.,Whitehead, Andrew J.
, p. 8535 - 8538 (2007/10/03)
A practical enantioselective synthesis of lamivudine 1 is described. A highly effective dynamic kinetic resolution of the 5-hydroxyoxathiolane, followed by chlorination and introduction of cytosine provides an efficient synthesis of lamivudine.
