4402-93-1

Basic information

• Product Name: methyl 3-(2-chloro-3-methoxyphenyl)-5-methylisoxazole-4-carboxylate
• Synonyms: methyl 3-(2-chloro-3-methoxyphenyl)-5-methylisoxazole-4-carboxylate
• CAS NO: 4402-93-1
• Molecular Weight: 281.696
• Mol File: 4402-93-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-(2-chloro-3-methoxyphenyl)-5-methylisoxazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(2-chloro-3-methoxyphenyl)-5-methylisoxazole-4-carboxylate(4402-93-1)
• EPA Substance Registry System: methyl 3-(2-chloro-3-methoxyphenyl)-5-methylisoxazole-4-carboxylate(4402-93-1)

Safety Data

• Hazardous Substances Data: 4402-93-1(Hazardous Substances Data)

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 54881-49-1 2-chloro-3-methoxy benzaldehyde 

Downstream Products

• 4414-61-3 3-(2-chloro-3-hydroxy-phenyl)-5-methyl-isoxazole-4-carbonyl chloride 
• 4414-55-5 3-(2-chloro-3-hydroxy-phenyl)-5-methyl-isoxazole-4-carboxylic acid 
• 4402-94-2 3-(2-chloro-3-methoxy-phenyl)-5-methyl-isoxazole-4-carboxylic acid 

Relevant articles and documents

1-(4-(ISOXAZOL-5-YL)-1H-PYRAZOL-1-YL)-2-METHYLPROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS IL-17 AND IFN-GAMMA INHIBITORS FOR TREATING AUTOIMMUNE DISEASES AND CHRONIC INFLAMMATION

The present invention relates to compounds of the general formula (I), and the pharmaceutically acceptable salts and solvates thereof, wherein Ar, Z and Y are as described herein and R1 is a group of the structure (formula (II)), wherein n is 0 or 1; R2 is H, deuterium or methyl; R3 is methyl, trilluoromethyl, ethyl, or taken with R2 together forms a cyclopropyl group, or R3 forms a methylene bridge to the carbon atom marked *, which are suitable for the treatment of autoimmune diseases and chronic inflammation.