440353-76-4Relevant academic research and scientific papers
An enantioselective synthesis of differentially protected erythro-α,β-diamino acids and its application to the synthesis of an analogue of rhodopeptin B5
Durham, Timothy B.,Miller, Marvin J.
, p. 35 - 42 (2007/10/03)
Methodology for the enantioselective synthesis of differentially protected erythro-α,β-diamino acids from N-tosyloxy β-lactams is reported. The requisite N-tosyloxy β-lactams are readily available from simple β-keto esters. The reported approach is flexible and compatible with a variety of functional groups. The synthetic utility of the method is demonstrated through its application to the preparation of an analogue of the antifungal cyclic peptide rhodopeptin B5.
