441012-22-2

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-BROMOPHENYL)-1H-PYRROLO[2,3-B]PYRIDINE is used as a building block for the synthesis of various pharmaceutical compounds due to its structural features and reactivity. Its unique heterocyclic structure may confer specific biological activities, making it a valuable compound for the development of new drugs.
Used in Agrochemical Industry:
1-(4-BROMOPHENYL)-1H-PYRROLO[2,3-B]PYRIDINE is used as a building block for the synthesis of various agrochemical compounds. Its structural features and reactivity make it a potential candidate for the development of new agrochemicals with improved properties and efficacy.
Used in Medicinal Chemistry Research:
1-(4-BROMOPHENYL)-1H-PYRROLO[2,3-B]PYRIDINE is used as a compound of interest for medicinal chemistry research. Its unique heterocyclic structure and potential biological activities make it a promising candidate for the study of new drug targets and the development of novel therapeutic agents.
Used in Chemical Modifications:
1-(4-BROMOPHENYL)-1H-PYRROLO[2,3-B]PYRIDINE is used as a compound for further chemical modifications through its bromine group. This allows for the tailoring of its properties for specific applications, such as the development of new drugs or agrochemicals with improved characteristics and performance.

InChI:InChI=1/C13H9BrN2/c14-11-3-5-12(6-4-11)16-9-7-10-2-1-8-15-13(10)16/h1-9H

Upstream product

• 271-63-6 7-Azaindole 
• 106-37-6 1.4-dibromobenzene 
• 589-87-7 1,4-bromoiodobenzene 

Downstream Products

• 467238-87-5 4-(N-7-azaindolyl)phenylacetylene 
• 792909-37-6 1-(4-trimethylstannylphenyl)pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

N-Arylation of azaindoles in LiCl-mediated catalytic CuI reactions

N-Arylation of 5- and 7-azaindoles was achieved in LiCl-mediated catalytic CuI reactions at 120 °C with moderate to high yields. N-Arylation can be performed with various arylhalides, such as phenyl, pyridine, quinoline, thiophen, and thiazole moieties.

Copper-catalyzedortho-selective direct sulfenylation ofN-aryl-7-azaindoles with disulfides

A copper-catalyzed direct C-H chalcogenation ofN-aryl-azaindoles with disulfides is described. This transformation was performed using Earth abundant Cu(OAc)2as a catalyst, benzoic acid as an additive, air as a terminal oxidant, and readily available diaryl and dialkyldisulfides (or diselenide) as chalcogenation reagents. High functional group tolerance and excellent regioselectivity are demonstrated by the efficient preparation of a wide range ofortho-sulfenylation-7-azaindoles.

Rhodium-catalyzed regioselective C-H chlorination of 7-azaindoles using 1,2-dichloroethane

An unexpected rhodium-catalyzed regioselective C-H chlorination of 7-azaindoles was developed using 1,2-dichloroethane (DCE) as a chlorinating agent and 7-azaindole as the directing group. This protocol provides an efficient access to ortho-chlorinated azaindoles with operational simplicity, good functional group tolerance, and a wide substrate scope. (Chemical Equation Presented).

Syntheses and photophysical properties of rigid-rod conjugated compounds based on N-7-azaindole and 2,2′-dipyridylamine

Rigid-rod conjugated compounds based on N-7-azaindole and 2,2′-dipyridylamine functional groups have been synthesized as potential compounds for molecular electronic devices via Pd-mediated Sonogashira couplings. Their photoluminescent properties have been investigated.