441016-98-4

Usage

Structure

Tricyclic, pentalenone core with a hexahydro-5-methoxysubstituent

Stereochemistry

Alpha orientation of substituents at positions 3a, 5, and 6a

Properties

The specific properties of 2(1H)-Pentalenone, hexahydro-5-methoxy-,(3a-alpha-,5-alpha-,6a-alpha-)-(9CI) are not provided in the material.

Potential applications

Pharmaceutical, perfumery, and organic synthesis industries. Further research is required to understand its full potential.

Upstream product

• 481047-54-5 (3'aα,5'α,6'aα)-hexahydro-5'-methoxy-5,5-dimethylspiro[1,3-dioxane-2,2'(1'H)-pentalene] 

Downstream Products

• 600700-65-0 (4aα,6α,7aα)-hexahydro-6-methoxycyclopenta[c]pyran-3(1H)-one 
• 600700-65-0 4aS-(4aα,6α,7aα)-hexahydro-6-methoxy-cycopenta[c]pyran-3(1H)-one 

Relevant academic research and scientific papers

Synthesis and biological evaluation of bicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes

A series of novel bicyclo[3.3.0]octane derivatives have been synthesized and found to be dipeptidyl peptidase 4 (DPP-4) inhibitors. Compounds 10a and 10b demonstrate good efficacies in oral glucose tolerance tests.

Dicyclooctane Derivatives, Preparation Processes and Medical Uses Thereof

The present invention relates to new dicyclooctane derivates represented by general formula (I), preparation processes and pharmaceutical compositions containing them, and to uses for treatment especially for dipeptidyl peptidase inhibitor (DPPIV), in which each substituent group of general formula (I) is as defined in specification.

DICYCLOOCTANE DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF

The present invention relates to new dicyclooctane derivates represented by general formula (I), preparation processes and pharmaceutical compositions containing them, and to uses for treatment especially for dipeptidyl peptidase inhibitor (DPPIV), in which each substituent group of general formula (I) is as defined in specification

An enantiodivergent trend in microbial Baeyer-Villiger oxidations of functionalized pentalenones by recombinant whole cells expressing monooxygenases from Acinetobacter and Pseudomonas

We have investigated the microbial Baeyer-Villiger oxidations of pentalenones by recombinant whole cells expressing cyclohexanone monooxygenase from Acinetobacter and cyclopentanone monooxygenase from Pseudomonas. The two enzymes display a distinguishable

Whole-cell mediated Baeyer-Villiger oxidation of functionalized bicyclo[3.3.0]ketones by recombinant E. coli

Recombinant whole cells of Escherichia coli overexpressing Acinetobacter sp. NCIMB 9871 cyclohexanone monooxygenase (E.C. 1.14.13.22) have been utilized for the Baeyer-Villiger oxidation of functionalized bicyclo[3.3.0]ketones. Prochiral substrates were d