441351-32-2

Basic information

• Product Name: (Z)-Pterostilbene
• Synonyms: (Z)-Pterostilbene;4-[(1Z)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol;cis-Pterostilbene
• CAS NO: 441351-32-2
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.299
• Mol File: 441351-32-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 420.4 °C at 760 mmHg
• Flash Point: 208.1 °C
• Appearance: /
• Density: 1.169
• Vapor Pressure: 1.15E-07mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: (Z)-Pterostilbene(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-Pterostilbene(441351-32-2)
• EPA Substance Registry System: (Z)-Pterostilbene(441351-32-2)

Safety Data

• Hazardous Substances Data: 441351-32-2(Hazardous Substances Data)

Usage

General Description

(Z)-Pterostilbene is a natural compound found in various plants, including blueberries and grapes. It is a derivative of resveratrol and exhibits similar antioxidant and anti-inflammatory properties. (Z)-Pterostilbene has been studied for its potential therapeutic benefits, including its ability to protect against oxidative stress, reduce inflammation, and support healthy aging. It has also shown promise in improving cognitive function and protecting against neurodegenerative diseases. Additionally, (Z)-Pterostilbene has been investigated for its potential anti-cancer effects and its ability to support cardiovascular health. Overall, (Z)-Pterostilbene is a promising natural compound with potential health benefits and therapeutic applications.

InChI:InChI=1/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3-

Upstream product

• 537-42-8 3,5-dimethoxy-4'-hydroxy-trans-stilbene 
• 705-76-0 3,5-dimethoxybenzyl alcohol 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 6652-32-0 3,5-dimethoxybenzylchloride 
• 54900-97-9 3,5-dimethoxybenzyltriphenylphosphonium chloride 
• 123-08-0 4-hydroxy-benzaldehyde 
• 1012-12-0 4-(trimethylsiloxy)benzaldehyde 
• 877-88-3 3,5-dimethoxybenzyl bromide 
• 24131-30-4 (3,5-dimethoxybenzyl)triphenylphosphonium bromide 
• 120743-99-9 p-[(tert-butyldimethylsilyl)oxy]benzaldehyde 
• 441351-30-0 (Z)-4'-(tert-butyldimethylsilyloxy)-3,5-dimethoxystilbene 

Downstream Products

• 94608-23-8 (Z)-1-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)ethene 
• 537-42-8 3,5-dimethoxy-4'-hydroxy-trans-stilbene 
• 441351-38-8 Phosphoric acid dibenzyl ester 4-[(Z)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenyl ester 

Relevant articles and documents

A focused multiple reaction monitoring (MRM) quantitative method for bioactive grapevine stilbenes by ultra-high-performance liquid chromatography coupled to triple-quadrupole mass spectrometry (UHPLC-QqQ)

Grapevine stilbenes are a family of polyphenols which derive from trans-resveratrol having antifungal and antimicrobial properties, thus being considered as phytoalexins. In addition to their diverse bioactive properties in animal models, they highlight a strong potential in human health maintenance and promotion. Due to this relevance, highly-specific qualitative and quantitative methods of analysis are necessary to accurately analyze stilbenes in different matrices derived from grapevine. Here, we developed a rapid, sensitive, and specific analysis method using ultra-high-performance liquid chromatography coupled to triple-quadrupole mass spectrometry (UHPLC-QqQ) in MRM mode to detect and quantify five grapevine stilbenes, trans-resveratrol, trans-piceid, trans-piceatannol, trans-pterostilbene, and trans-?-viniferin, whose interest in relation to human health is continuously growing. The method was optimized to minimize in-source fragmentation of piceid and to avoid co-elution of cis-piceid and trans-resveratrol, as both are detected with resveratrol transitions. The applicability of the developed method of stilbene analysis was tested successfully in different complex matrices including cellular extracts of Vitis vinifera cell cultures, reaction media of biotransformation assays, and red wine.

Complete NMR data of methoxylated cis- and trans-stilbenes as well as 1,2-diphenylethanes

Resveratrol is a polyphenol isolated from many natural sources including grapes, mulberries, eucalyptus, spruce, lilies, and peanuts. The hydroxyl groups in polyphenols can be substituted with various functional groups, allowing production of multiple derivatives. NMR spectroscopy is used to identify new derivatives. Since the complete NMR data of the known derivatives can be useful for identification of the newly isolated derivatives, here, we report the synthesis of 14 methoxylated stilbenes and four 1,2-diphenylethanes and their NMR data.

Synthesis of radiolabeled stilbene derivatives as new potential PET probes for aryl hydrocarbon receptor in cancers

New carbon-11 and fluorine-18 labeled stilbene derivatives, cis-3,5-dimethoxy-4′-[11C]methoxystilbene (4′-[11C]8a), cis-3,4′,5-trimethoxy-3′-[11C]methoxystilbene (3′-[11C]8b), trans-3,5-dimethoxy-4′-[11C]methoxystilbene (4′-[11C]10a), trans-3,4′,5-trimethoxy-3′-[11C]methoxystilbene (3′-[11C]10b), cis-3,5-dimethoxy-4′-[18F]fluorostilbene (4′-[18F]12a), and trans-3,5-dimethoxy-4′-[18F]fluorostilbene (4′-[18F]13a), were designed and synthesized as potential PET probes for aryl hydrocarbon receptor (AhR) in cancers.