441766-52-5Relevant academic research and scientific papers
Asymmetric synthesis of β-amino-α-hydroxyphosphinic acid derivatives through hydrophosphinylation of α-amino aldehydes
Yamagishi, Takehiro,Suemune, Kenji,Yokomatsu, Tsutomu,Shibuya, Shiroshi
, p. 2577 - 2583 (2007/10/03)
The diastereoselective synthesis of β-amino-α-hydroxyphosphinates was achieved by hydrophosphinylation of N,N-dibenzyl-α-amino aldehydes with ethyl ethylphosphinate catalyzed by (S)-ALB. The hydrophosphinylation using ethyl phosphinate afforded both syn- and anti-β-amino-α-hydroxy-H-phosphinates with high diastereoselectivities by tuning the chirality of ALB.
Diastereoselective synthesis of chiral β-amino-α-hydroxy-H-phosphinates through hydrophosphinylation of α-amino aldehydes
Yamagishi, Takehiro,Suemune, Kenji,Yokomatsu, Tsutomu,Shibuya, Shiroshi
, p. 5033 - 5036 (2007/10/03)
A stereodivergent synthesis of β-amino-α-hydroxy-H-phosphinates was achieved by ALB-catalyzed hydrophosphinylation of N,N-dibenzyl-α-amino aldehydes tuning the chirality of the catalyst.
