441773-68-8

Basic information

• Product Name: 3-(2-hydroxy-ethylidene)-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 441773-68-8
• Molecular Weight: 213.277
• Mol File: 441773-68-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(2-hydroxy-ethylidene)-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-hydroxy-ethylidene)-pyrrolidine-1-carboxylic acid tert-butyl ester(441773-68-8)
• EPA Substance Registry System: 3-(2-hydroxy-ethylidene)-pyrrolidine-1-carboxylic acid tert-butyl ester(441773-68-8)

Safety Data

• Hazardous Substances Data: 441773-68-8(Hazardous Substances Data)

Upstream product

• 664364-28-7 tert-butyl 3-(2-ethoxy-2-oxoethylidene)pyrrolidine-1-carboxylate 
• 101385-93-7 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 441773-67-7 tert-butyl 3-(2-methoxy-2-oxoethylidene)pyrrolidine-1-carboxylate 

Downstream Products

• 441773-73-5 3-ethoxycarbonylmethyl-3-(4-hydroxy-phenylsulfanylmethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 441773-75-7 3-ethoxycarbonylmethyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 160132-53-6 tert-butyl-3-(2-methylsulfonyloxyethyl)pyrrolidine-1-carboxylate 

Relevant articles and documents

AMINOPYRIDINE COMPOUNDS AND METHODS FOR THE PREPARATION AND USE THEREOF

The present invention relates generally to therapeutics targeting the bacterium Porphyromonas gingivalis, including its proteases arginine gingipain A/B (Rgp), and their use for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease. In certain embodiments, the invention provides compounds according to Formula I and Formula III, as described herein, and pharmaceutically acceptable salts thereof.