441785-21-3 Usage
Uses
Used in Pharmaceutical Industry:
PMEA is used as an antiviral agent for the treatment of viral infections, specifically targeting HIV and hepatitis B virus. Its application is based on its ability to inhibit viral replication by blocking the action of viral DNA polymerase, which is crucial for the virus to make copies of its genetic material. This action helps in controlling the spread of the virus within the host.
Used in Research and Development:
In the field of virology and pharmaceutical research, PMEA is utilized as a subject of study for understanding the mechanisms of viral replication and the development of antiviral therapies. Its unique mode of action provides insights into the design of new antiviral drugs and the potential for combination therapies with existing treatments.
Used in HIV Treatment:
PMEA is used as a therapeutic agent in the management of HIV infection. It is considered for inclusion in antiretroviral treatment regimens due to its capacity to impede the replication of the virus, which can contribute to lowering viral loads and potentially slowing disease progression.
Used in Hepatitis B Treatment:
Similarly, PMEA is explored for its application in treating hepatitis B virus infections. Its antiviral properties make it a candidate for therapeutic intervention, potentially leading to reduced viral replication and improved liver health in affected individuals.
Overall, P-[[[1-[(6-AMINO-9H-PURIN-9-YL)METHYL]CYCLOPROPYL]OXY]METHYL]-PHOSPHONIC ACID, or PMEA, is a versatile compound with significant implications in the medical and scientific spheres, particularly in the fight against viral diseases. Its applications are varied, ranging from direct patient treatment to contributing to the advancement of antiviral drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 441785-21-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,1,7,8 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 441785-21:
(8*4)+(7*4)+(6*1)+(5*7)+(4*8)+(3*5)+(2*2)+(1*1)=153
153 % 10 = 3
So 441785-21-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N5O4P/c11-8-7-9(13-4-12-8)15(5-14-7)3-10(1-2-10)19-6-20(16,17)18/h4-5H,1-3,6H2,(H2,11,12,13)(H2,16,17,18)
441785-21-3Relevant academic research and scientific papers
NUCLEOSIDE PHOSPHONATE DERIVATIVES USEFUL IN THE TREATMENT OF HIV INFECTIONS
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, (2008/06/13)
The present invention relates to a method of treating HIV infections by administering a nucleoside phosphonate derivative represented by formula (I).
