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4418-26-2 Usage


Sodium dehydroacetate, also known as dehydroacetic acid sodium salt (DHA-S), is a new generation food preservative and food additive. It is the sodium salt of dehydroacetate and has a wide spectrum of antimicrobial activity, making it effective against both bacteria and fungi. Sodium dehydroacetate is used extensively in various food products such as sauce, fruit, bread, cake, moon cake, margarine, and beverages. Additionally, it is recognized by major cosmetic, toiletry, and fragrance regulatory authorities worldwide for use in cosmetic products as a preservative and antimicrobial agent. It also functions as an anticoagulant agent by depleting the blood level of vitamin K.


Used in Food Industry:
Sodium dehydroacetate is used as a preservative for fruits, vegetables, fruit juice, honey, beer, milk, protein, and fat products. It helps maintain the freshness and quality of these products while preventing spoilage caused by microbial growth.
Used in Human and Veterinary Medicine:
In medicine, sodium dehydroacetate serves as a bactericide and fungicide, effectively treating bacterial and fungal infections. Its antimicrobial properties make it a valuable component in various medical applications.
Used in Cosmetic and Personal Care Products:
Sodium dehydroacetate is used in cosmetic products as a preservative and antimicrobial agent. It is a key ingredient in products like Geogard(R) 111S preservative, which is based on dehydroacetic acid (DHA) and its sodium salt form (NaDHA). This preservative is recognized by major regulatory authorities for its safety and effectiveness in cosmetic and personal care products.
Used in Combination with Parabens:
Sodium dehydroacetate can be used in combination with parabens, another type of preservative, to provide enhanced preservation against bacteria and fungi. This combination is useful in various applications where a broader spectrum of antimicrobial activity is required.
However, it is important to note that sodium dehydroacetate may cause skin irritation in some individuals, and its use should be carefully considered based on the specific application and potential sensitivities.

Air & Water Reactions

Water soluble.

Reactivity Profile

Sodium dehydroacetate reacts with acids. May react viogrously with strong oxidizing acids.

Flammability and Explosibility


Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. An eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Na2O


Forester, John. "Preservative solutions containing sodium dehydroacetate with or without sodium borate decahydrate and/or disodium edetate." US, US4248634. 1981. Sakaguchi, Yuka, et al. "Anticoagulant effect of sodium dehydroacetate (DHA-S) in rats." Journal of Applied Toxicology 28.4(2008):524-529. Ye, Yinzhi. "Use of Sodium Dehydroacetate in Food." China Food Additives (2002).

Check Digit Verification of cas no

The CAS Registry Mumber 4418-26-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,1 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4418-26:
82 % 10 = 2
So 4418-26-2 is a valid CAS Registry Number.

4418-26-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (B21060)  Sodium dehydroacetate, 97%   

  • 4418-26-2

  • 100g

  • 500.0CNY

  • Detail
  • Alfa Aesar

  • (B21060)  Sodium dehydroacetate, 97%   

  • 4418-26-2

  • 500g

  • 1823.0CNY

  • Detail
  • Alfa Aesar

  • (B21060)  Sodium dehydroacetate, 97%   

  • 4418-26-2

  • 2500g

  • 7105.0CNY

  • Detail
  • Sigma-Aldrich

  • (PHR1609)  Sodium Dehydroacetic Acid  pharmaceutical secondary standard; traceable to USP

  • 4418-26-2

  • PHR1609-10G

  • 4,312.04CNY

  • Detail
  • Aldrich

  • (689521)  Dehydroaceticacidsodiumsalt  Lonza quality, 99.0-100.3% (w/w) (T)

  • 4418-26-2

  • 689521-1KG

  • 3,291.21CNY

  • Detail
  • Aldrich

  • (689521)  Dehydroaceticacidsodiumsalt  Lonza quality, 99.0-100.3% (w/w) (T)

  • 4418-26-2

  • 689521-10KG

  • 14,964.30CNY

  • Detail
  • Aldrich

  • (689521)  Dehydroaceticacidsodiumsalt  Lonza quality, 99.0-100.3% (w/w) (T)

  • 4418-26-2

  • 689521-40KG

  • 44,963.10CNY

  • Detail
  • Aldrich

  • (30750)  Dehydroaceticacidsodiumsalt  ≥98.0% (NT)

  • 4418-26-2

  • 30750-100G-F

  • 522.99CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017


1.1 GHS Product identifier

Product name Sodium dehydroacetate

1.2 Other means of identification

Product number -
Other names harven

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4418-26-2 SDS

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