4418-50-2Relevant academic research and scientific papers
Synthesis, characterization, and antimicrobial studies of new rigid linker-based bispyrazolines
Yusuf, Mohamad,Samdhian, Varsha,Jain, Payal
, p. 260 - 266 (2015)
The bispyrazolines 4a-4e were synthesized from the cyclization reaction of bischalcones 3a-3e with phenyl hydrazine by refluxing under alcoholic medium in the presence of glacial acetic acid. The bischalcones were obtained from the Claisen-Schmidt reactio
Multicomponent synthesis of new bis(pyranopyrazoles) and their antimicrobial–antioxidant evaluations
Yusuf, Mohamad,Thakur, Saloni
, p. 119 - 128 (2019/05/15)
One-pot, three-component reactions were utilized to obtain a series of new symmetrical bis(pyranopyrazoles) built around six rigid linkers in good yields and in the short durations under normal conditions. The structures of the prepared compounds were confirmed using their IR, 1H-NMR, 13C-NMR and ESI-MS spectral parameters. The bis(pyranopyrazoles) 3b and 3f exhibited significant antimicrobial action against Klebsiella pneumoniae, Fusarium oxysporum and Penicillium glabrum at a minimum inhibitory concentration (MIC) value of 3.12 μg mL-1, which is equivalent to the MIC of the standard drug. trans-Butene-linked bis(pyranopyrazole) 3f was also associated with a good radical scavenging activity similar to that of ascorbic acid (a standard antioxidant).
Synthesis and antimicrobial studies of new N,N'-[5,5'-{2,2'-(bis-alkoxy) bis(2,1-phenylene)]bis(4-acetyl-4,5-dihydro-1,3,4-thiadiazole-5, 2-diyl)]diacetamide
Yusuf, Mohamad,Solanki, Indu,Jain, Payal
experimental part, p. 703 - 715 (2012/09/07)
The bisthiadiazolines 4a(a'-f ') and 4b(a'-f ') built around the various rigid chains have been synthesized in good yields by refluxing bisthiosemicarbazones 3a(a'-f ') and 3b(a'-f ') in acetic anhydride medium. The reaction of bisaldehydes 2a(a'-f ') and
