4419-71-0Relevant academic research and scientific papers
A modified synthesis and serological evaluation of neoglycoproteins containing the natural disaccharide of PGL-I from Mycobacterium leprae
Zhang, Jian,Chatterjee, Delphi,Brennan, Patrick J.,Spencer, John S.,Liav, Avraham
, p. 3250 - 3253 (2010)
In order to generate substantial amounts of neoglycoconjugate needed for commercialization of diagnostic kits and high-throughput detection of leprosy, we developed a facile and high-yield synthesis of the corresponding disaccharide. Herein, the non-reduc
An n.m.r. and conformational analysis of the terminal trisaccharide from the serologically active glycolipid of Mycobacterium leprae in different solvents
Bock, Klaus,Hvidt, Torsten,Marino-Albernas, J.,Verez-Bencomo, Vincente
, p. 33 - 45 (2007/10/02)
The 1H- and 13C-n.m.r. spectra of allyl 2-O--3-O-methyl-α-L-rhamnopyranoside (3), a glycoside of the terminal trisaccharide found in the phenolic glycolipid I from Mycobacterium leprae, and those of the two component disaccharides, allyl 4-O-(3,6-di-O-methyl-β-D-glucopyranosyl)-2,3-di-O-methyl-α-L-rhamnopyranoside (1) and allyl 2-O-(2,3-di-O-methyl-α-L-rhamnopyranosyl)-3-O-methyl-α-L-rhamnopyranoside (2) have been assigned completely by 1D and 2D techniques.The preferred conformations, determined by chemical shift and n.O.e. studies, were different in D2O, CD3OD, and CDCl3.The preferred conformation of 3 accorded with the results of hard-sphere exo-anomeric (HSEA) calculations.
Preparation of Some Partially Methylated L-Rhamnosides and D-Ribosides
Batavyal, Lakshmi,Roy, Nirmolendu
, p. 499 - 500 (2007/10/02)
Partially methylated L-rhamnosides and D-ribosides have been prepared using limited amounts (25 to 35percent less than that needed for complete methylation) of methylating reagents, and characterized by GLC or GLC/MS.Methyl 2,3-di-O-methyl-α-L-rhamnoside has also been prepared by a modified method of Hough and Jones .
