4420-43-3Relevant academic research and scientific papers
Metal-free oxidative cyclization of alkynyl aryl ethers to benzofuranones
Graf, Katharina,Ruehl, Carmen L.,Rudolph, Matthias,Rominger, Frank,Hashmi, A. Stephen K.
, p. 12727 - 12731 (2013)
Readily available phenols can be converted into substituted aryl alkynyl ethers, which react with an N-oxide as an oxidant and catalytic amounts of a Bronsted acid to provide benzofuranones. If non-terminal alkynyl ethers are applied, a 1,2-hydride shift takes place and phenyl acrylates are obtained. Thus activated alkynes can serve as α-oxy carbene precursors even in the absence of a metal catalyst. Copyright
