442159-50-4

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 442159-47-9 (8E,12E)-(2S,6S,7S,10S,11R)-7,11-Bis-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-2,6,8,10,12-pentamethyl-3-oxo-2-trimethylsilanyloxy-tetradeca-8,12-dienoic acid benzyl ester 
• 442159-48-0 (4E,8E,12E)-(2S,6S,7S,10S,11R)-7,11-Bis-(tert-butyl-dimethyl-silanyloxy)-2,6,8,10,12-pentamethyl-3-oxo-2-trimethylsilanyloxy-tetradeca-4,8,12-trienoic acid benzyl ester 
• 442159-44-6 Benzoic acid (5E,9E)-(1S,3R,4S,7S,8R)-4,8-bis-(tert-butyl-dimethyl-silanyloxy)-1,3,5,7,9-pentamethyl-2-oxo-undeca-5,9-dienyl ester 
• 442159-45-7 (6E,10E)-(2S,4S,5S,8S,9R)-5,9-Bis-(tert-butyl-dimethyl-silanyloxy)-4,6,8,10-tetramethyl-dodeca-6,10-diene-2,3-diol 
• 442159-43-5 Benzoic acid (5E,9E)-(1S,3R,4S,7S,8R)-8-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-1,3,5,7,9-pentamethyl-2-oxo-undeca-5,9-dienyl ester 
• 442159-46-8 (4E,8E)-(2R,3S,6S,7R)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-2,4,6,8-tetramethyl-deca-4,8-dienal 
• 442159-38-8 (R)-4-benzyl-3-((2R,3R,E)-3-(tert-butyldimethylsilyloxy)-2,4-dimethylhex-4-enoyl)oxazolidin-2-one 
• 442159-37-7 (R)-4-benzyl-3-((2R,3R,E)-3-hydroxy-2,4-dimethylhex-4-enoyl)oxazolidin-2-one 
• 442159-40-2 (2E,6E)-(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2,4,6-trimethyl-octa-2,6-dienoic acid ethyl ester 
• 442159-41-3 (2E,6E)-(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2,4,6-trimethyl-octa-2,6-dien-1-ol 
• 442159-42-4 (2E,6E)-(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2,4,6-trimethyl-octa-2,6-dienal 
• 442159-39-9 3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enethioic acid S-ethyl ester 
• 760984-24-5 (2R,3R,4E)-3-(tert-butyldimethylsilyloxy)-2,4-dimethyl-4-hexenal 

Relevant academic research and scientific papers

Synthetic studies on a cyclic hexadepsipeptide GE3: Stereoselective construction of the acyl side chain segment

Stereoselective synthesis of the acyl side chain segment 2 of GE3 (1), a potent inhibitor of cell progression of the cell cycle from the G1 to S phase, has been achieved by using Sharpless' asymmetric dihydroxylation and Evans' and Paterson's stereoselective aldol methodologies.