442202-15-5

Basic information

• Product Name: dimethyl (2R,3S,5R,6S)-(+)-6-(tert-butyldiphenylsilyloxymethyl)-5-ethyl-3-vinylpiperidine-1,2-dicarboxylate
• Synonyms: dimethyl (2R,3S,5R,6S)-(+)-6-(tert-butyldiphenylsilyloxymethyl)-5-ethyl-3-vinylpiperidine-1,2-dicarboxylate
• CAS NO: 442202-15-5
• Molecular Weight: 523.745
• Mol File: 442202-15-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl (2R,3S,5R,6S)-(+)-6-(tert-butyldiphenylsilyloxymethyl)-5-ethyl-3-vinylpiperidine-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl (2R,3S,5R,6S)-(+)-6-(tert-butyldiphenylsilyloxymethyl)-5-ethyl-3-vinylpiperidine-1,2-dicarboxylate(442202-15-5)
• EPA Substance Registry System: dimethyl (2R,3S,5R,6S)-(+)-6-(tert-butyldiphenylsilyloxymethyl)-5-ethyl-3-vinylpiperidine-1,2-dicarboxylate(442202-15-5)

Safety Data

• Hazardous Substances Data: 442202-15-5(Hazardous Substances Data)

Upstream product

• 442202-33-7 (2R,3R)-3-(tetrahydropyran-2-yloxymethyl)pentane-1,2-diol 
• 442202-32-6 (2S)-2-(2-ethylbut-3-enyloxy)tetrahydropyrane 
• 442202-28-0 methyl (2S,3R)-(-)-2-(tert-butyldiphenylsilyloxymethyl)-3-ethyl-6-trifluoromethanesulfonyloxy-3,4-dihydro-2H-pyridine-1-carboxylate 
• 442202-13-3 (5R,6S)-(+)-6-(tert-butyldiphenylsilyloxymethyl)-5-ethylpiperidin-2-one 
• 117935-51-0 (R)-1-O-acetyl-2-ethyl-1,3-propanediol 
• 917-57-7 vinyllithium 
• 442202-14-4 dimethyl (5R,6S)-(-)-6-(tert-butyldiphenylsilyloxymethyl)-5-ethyl-5,6-dihydro-4H-pyridine-1,2-dicarboxylate 
• 1112-56-7 tetravinyltin (IV) 
• 442202-35-9 (2S,3S)-1-(tert-butyldiphenylsilyloxy)-3-(tetrahydropyran-2-yloxymethyl)pentan-2-azide 
• 442202-34-8 (2R,3R)-1-(tert-butyldiphenylsilyloxy)-3-(tetrahydropyran-2-yloxymethyl)pentan-2-ol 
• 442202-36-0 ethyl (4R,5S)-5-azide-6-(tert-butyldiphenylsilyloxy)-4-ethyl-2-hexenoate 

Downstream Products

• 1026547-61-4 (2S,3R,5S,6R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-ethyl-6-formyl-5-vinyl-piperidine-1-carboxylic acid methyl ester 
• 442202-18-8 methyl (2S,3R,5R,6S)-(+)-2-(tert-butyldiphenylsilyloxymethyl)-3,5-diethyl-6-(3-hydroxypropyl)piperidine-1-carboxylate 
• 442202-30-4 methyl (2S,3R,5R,6S)-(-)-2-(tert-butyldiphenylsilyloxymethyl)-3,5-diethyl-6-(3-methoxymethoxypropyl)piperidine-1-carboxylate 
• 442202-29-1 methyl (2S,3R,5S,6R)-(-)-2-(tert-butyldiphenylsilyloxymethyl)-3-ethyl-6-(2-ethoxycarbonylvinyl)-5-vinylpiperidine-1-carboxylate 
• 442202-16-6 methyl (2S,3R,5S,6R)-(+)-2-(tert-butyldiphenylsilyloxymethyl)-3-ethyl-6-hydroxymethyl-5-vinylpiperidine-1-carboxylate 

Relevant articles and documents

Stereodivergent synthesis of the 2,3,5,6-tetrasubstituted piperidine ring system: An application to the synthesis of alkaloids

Stereodivergent synthesis of the 2,3,5,6-tetrasubstituted piperidine ring system has been achieved by sequential stereocontrolled Michael-type conjugate addition reaction of appropriate enaminoesters. This methodology has been applied to the total synthes