4423-47-6

Usage

Uses

Used in Pharmaceutical Applications:
[1,1':4',1''-Terphenyl]-2',3',5'-triol is used as a potential therapeutic agent for its antioxidant and anti-inflammatory properties, which may contribute to the treatment or management of various diseases and conditions.
Used in Chemical Synthesis:
[1,1':4',1''-Terphenyl]-2',3',5'-triol is used as a building block in the synthesis of novel organic compounds, potentially leading to the development of new pharmaceuticals, agrochemicals, or other specialty chemicals.
Used in Polymer Production:
[1,1':4',1''-Terphenyl]-2',3',5'-triol is used as a component in the production of polymers with specific properties, such as enhanced thermal stability or mechanical strength, for various industrial applications.
Used in Material Science:
[1,1':4',1''-Terphenyl]-2',3',5'-triol is used to enhance the thermal and mechanical properties of composites, making it a valuable additive in the development of advanced materials for various industries, including aerospace, automotive, and electronics.
Used in the Plant Industry:
[1,1':4',1''-Terphenyl]-2',3',5'-triol is used as a natural compound found in various plants, which may have potential applications in the study of plant biochemistry, ecology, or as a source of bioactive compounds for pharmaceutical or agricultural applications.

Upstream product

• 548-59-4 2,5-dihydroxy-3,6-diphenyl-1,4-benzoquinone 

Downstream Products

• 20958-04-7 Terferol 
• 20958-07-0 3-Hydroxy-6-methoxy-2,5-diphenyl-1-<α-methoxycarbonyl-p-(p-toluolsulfonyloxy)-benzyliden>-cyclohexadien-2,5-on-(4) 
• 20958-09-2 3,4-Dihydroxy-1-methoxy-2-phenyl-9-(p-hydroxyphenyl)-9-methoxycarbonyl-fluoren 
• 21164-86-3 2-Hydroxy-5,6,6-trimethoxy-1,4-diphenylcyclohexa-1,4-dien-3-on 

Relevant academic research and scientific papers

The coupled reaction catalyzed by EchB and EchC lead to the formation of the common 2′,3′,5′-trihydroxy-benzene core in echosides biosynthesis

p-Terphenyls represent a unique family of aromatic natural products generated by nonribosomal peptide synthetase-like (NRPS-like) enzyme. After formation of p-terphenyl skeleton, tailoring modifications will give rise to structural diversity and various biological activities. Here we demonstrated a two-enzyme (EchB, a short-chain dehydrogenase/reductase (SDR), and EchC, a nuclear transport factor 2 (NTF2)-like dehydratase) participated transformation from dihydroxybenzoquinone core to 2′,3′,5′-trihydroxy-benzene in the biosynthesis of echosides. Beginning with polyporic acid as substrate, successive steps of reduction-dehydration-reduction cascade catalyzed by EchB-EchC-EchB were concluded after in vivo gene disruption and in vitro bioassay experiments. These findings demonstrated a conserved synthesis pathway of 2′,3′,5′-trihydroxy-p-terphenyls in bacteria, such as Actinomycetes and Burkholderia. The parallel pathway in fungi has yet to be explored.