4428-00-6Relevant academic research and scientific papers
Convenient procedure for converting 1,3-dithiolane-2-thiones into 1,3-dithiolan-2-ones
Barbero, Margherita,Degani, Iacopo,Dughera, Stefano,Fochi, Rita,Piscopo, Laura
, p. 289 - 294 (2007/10/03)
1,3-Dithiolan-2-ones have been obtained by reaction of 1,3-dithiolane-2-thiones and epoxides in the presence of HBF4·Et2O. The reactions, carried out in anhydrous CH2Cl2 at 0-5°C→room temperature (Procedure A) or in anhydrous chlorobenzene at 0-5→80°C (Procedure B), gave product yields of 63-95%. By Procedure B it was also possible to isolate the intermediates 1-oxa-4,6,9-trithiaspiro[4,4]nonanes in good yields (66-85%). Reaction pathways are proposed.
