442850-71-7

Basic information

• Product Name: 1-tert-Butyl-1H-pyrazol-5-aMine
• Synonyms: 1-tert-Butyl-1H-pyrazol-5-aMine;5-AMino-1-tert-butylpyrazole;1H-Pyrazol-5-aMine, 1-(1,1-diMethylethyl)-
• CAS NO: 442850-71-7
• Molecular Formula: C₇H₁₃N₃
• Molecular Weight: 139.19822
• Mol File: 442850-71-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 247.5±13.0℃ (760 Torr)
• Flash Point: 103.5±19.8℃
• Appearance: /
• Density: 1.05±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 1-tert-Butyl-1H-pyrazol-5-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-Butyl-1H-pyrazol-5-aMine(442850-71-7)
• EPA Substance Registry System: 1-tert-Butyl-1H-pyrazol-5-aMine(442850-71-7)

Safety Data

• Hazardous Substances Data: 442850-71-7(Hazardous Substances Data)

Usage

General Description

1-tert-butyl-1H-pyrazol-5-amine is a chemical compound with the formula C7H14N4. It is a derivative of pyrazole and contains a tert-butyl functional group. The amine group in the molecule makes it a basic compound. 1-tert-butyl-1H-pyrazol-5-amine is commonly used in organic synthesis and pharmaceutical research as a building block for the production of various drugs and biologically active compounds. It is also used as a ligand in the coordination chemistry of transition metals. This chemical has potential applications in the development of new therapeutic agents and bioactive molecules. Additionally, it can be utilized in the development of new materials with specific properties and functions.

Upstream product

• 7400-27-3 tertbutylhydrazine hydrochloride 
• 920-37-6 2-Chloroacrylonitrile 

Downstream Products

• 442850-73-9 N-(2-tert-butyl-2H-pyrazol-3-yl)-benzamide 
• 1010086-61-9 N-(1-tert-butyl-1H-pyrazol-5-yl)-6-chloropyrazin-2-amine 
• 442850-79-5 N-(2-tert-butyl-2H-pyrazol-3-yl)-thiobenzamide 

Relevant articles and documents

5- OR 7-AZAINDAZOLES AS BETA-LACTAMASE INHIBITORS

The present invention relates to β-lactamase inhibitors having the following general formula (I): wherein R1-R4 and X1-X2 are defined in the specification, pharmaceutical composition thereof, and use thereof for the treatment of a bacterial infection, alone or in combination with β-lactam antibiotics and/or other antibiotics and/or other β-lactamase inhibitors.

Syntheses of 1-substituted-3-aminopyrazoles

A series of 1-substituted-3-aminopyrazoles were prepared via Chan-Lam coupling reactions, alkylation, and pyrazole ring formation.