442900-74-5

Upstream product

• 7432-21-5 N-carbobenzyloxy-L-tryptophane 
• 442900-70-1 2-amino-N-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3-(1H-indol-3-yl)-propionamide 
• 442900-68-7 Z-Trp-D-Leu-OMe 
• 442900-69-8 (R)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-4-methyl-pentanoic acid 
• 91578-89-1 2-((tert-butyldiphenylsilyl)oxy)ethanamine 
• 5845-53-4 (R)-leucine methyl ester hydrochloride 
• 442900-71-2 Z-Trp-D-Leu-Trp-2-(t-butyl-diphenylsilyloxy)-ethylamide 
• 442900-67-6 Z-Trp-2-(t-butyl-diphenylsilyloxy)-ethylamide 

Relevant academic research and scientific papers

Synthesis and functional studies of THF-gramicidin hybrid ion channels

THF-gramicidin hybrids 2-4 with the L-THF amino acid 1 in positions 11 and 12 and compounds 5-8 with the D-THF amino acid ent-1 in positions 10 and 11 were synthesized and their ion channel properties were studied by single-channel-current analysis. The r

Solution phase synthesis and purification of the minigramicidin ion channels and a succinyl-linked gramicidin

Peptides with alternating D- and L-configured residues as found in the natural ion channel active peptide gramicidin A (gA) are important building blocks for artificially engineered ion channels. We detail an optimised solution phase synthesis employing a