1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE, also known as 6-Methylsulfinylhexyl isothiocyanate (6-MSITC), is an isothiocyanate compound derived from Wasabia japonica (wasabi). It exhibits a range of biological activities, including the inhibition of nitric oxide production, aggregation of human platelets, and cell survival in various cancer cell lines. Additionally, it has demonstrated neuroprotective effects in a mouse model of Parkinson's disease and anti-metastatic properties in a murine melanoma model.
4430-35-7
Post Buying Request-
-
Basic information
- Product Name: 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE
- Synonyms: 6-METHYLSULFINYLHEXYL ISOTHIOCYANATE;1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE;6-HITC;6-MITC
- CAS NO:4430-35-7
- Molecular Formula: C8H15NOS2
- Molecular Weight: 205.34
- EINECS: N/A
- Product Categories: Aliphatics, Sulfur & Selenium Compounds
- Mol File: 4430-35-7.mol
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: 385.9±25.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.12±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: Refrigerator, under inert atmosphere
- Solubility: Chloroform (Sparingly), Methanol (Slightly)
- CAS DataBase Reference: 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE(CAS DataBase Reference)
- NIST Chemistry Reference: 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE(4430-35-7)
- EPA Substance Registry System: 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE(4430-35-7)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 4430-35-7(Hazardous Substances Data)
4430-35-7 Suppliers
Recommended suppliers
4430-35-7 Usage
Uses
Used in Pharmaceutical Industry:1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE is used as a potential therapeutic agent for various reasons, including its ability to inhibit glycogen synthase kinase-3β, reduce cell survival in multiple cancer cell lines, and exhibit neuroprotective effects in Parkinson's disease models.
Used in Cancer Research:
In cancer research, 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE is used as an inhibitor of various cancer cell lines, including breast, brain, colon, lung, ovarian, renal, and prostate cancers, due to its ability to reduce cell survival with a mean IC50 of 43.7 μM.
Used in Neurodegenerative Disease Research:
1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE is used as a neuroprotective agent in the context of Parkinson's disease, as it has been shown to reduce apoptosis of substantia nigral dopaminergic neurons and motor dysfunction in a mouse model induced by 6-OHDA.
Used in Anti-metastatic Applications:
In anti-metastatic research, 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE is used to reduce the number of lung metastases in a B16/F10 murine melanoma model, showcasing its potential in limiting cancer spread.
Check Digit Verification of cas no
The CAS Registry Mumber 4430-35-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,3 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.Calculate Digit Verification of CAS Registry Number 4430-35:
(6*4)+(5*4)+(4*3)+(3*0)+(2*3)+(1*5)=67
67 % 10 = 7
So 4430-35-7 is a valid CAS Registry Number.
4430-35-7Upstream product
4430-35-7Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 4430-35-7
1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE
