4433-52-7

Usage

Uses

Used in Rubber and Plastic Industry:
Benzothiazoline is used as a chemical intermediate for the production of rubber and plastic products, enhancing their durability and performance.
Used in Dye and Pharmaceutical Synthesis:
Benzothiazoline serves as an essential intermediate in the synthesis of dyes and pharmaceuticals, contributing to the development of various colorants and medicinal compounds.
Used in Industrial Applications:
Due to its strong antioxidant and UV-absorbing properties, benzothiazoline is used as an additive in various industrial applications to improve the stability and longevity of products.
Used in Anti-corrosive and Fungicidal Agents Manufacturing:
Benzothiazoline is utilized in the manufacturing of anti-corrosive agents and fungicides, providing protection against corrosion and fungal growth in different materials and surfaces.

InChI:InChI=1/C7H7NS/c1-2-4-7-6(3-1)8-5-9-7/h1-4,8H,5H2

Upstream product

• 50-00-0 formaldehyd 
• 137-07-5 2-amino-benzenethiol 
• 95-16-9 1,3-Benzothiazole 

Downstream Products

• 30831-94-8 benzothiazole-3-carboxylic acid ethyl ester 
• 72687-25-3 3-Chloracetyl-benzothiazolin 
• 21749-63-3 2-(methylamino)benzenethiol 
• 798567-70-1 (1'R,2R)-tert-butyl 2-(1-hydroxy-1-phenylmethyl)benzothiazolidine-3-carboxylate 
• 798567-64-3 (1'S,2R)-tert-butyl 2-(1-hydroxy-1-phenylmethyl)benzothiazolidine-3-carboxylate 
• 798567-67-6 (1'S,2R)-tert-butyl 2-[1-hydroxy-1-(4-chlorophenyl)methyl]benzothiazolidine-3-carboxylate 
• 798567-72-3 (1'R,2R)-tert-butyl 2-[1-hydroxy-1-(4-methoxyphenyl)methyl]benzothiazolidine-3-carboxylate 

Relevant academic research and scientific papers

Discovery of Dotinurad (FYU-981), a New Phenol Derivative with Highly Potent Uric Acid Lowering Activity

To derive new uricosuric agents, novel phenol derivatives were synthesized to overcome the disadvantages of benzbromarone (BBR), attributed by its structural features. Herein, we report the discovery of new phenol derivatives with a 1,1-dioxo-1,2-dihydro-

B(C6F5)3-Promoted hydrogenations of N-heterocycles with ammonia borane

A transition-metal-free method for the B(C6F5)3-promoted hydrogenations of N-heterocycles using ammonia borane under mild reaction conditions has been developed. The reaction affords a broad range of hydrogenated products in moderate to good yields. The enantioselective versions for the corresponding products were also investigated via our approach, showing good feasibility.

Metal-Free Hydrogen Atom Transfer from Water: Expeditious Hydrogenation of N-Heterocycles Mediated by Diboronic Acid

A hydrogenation of N-heterocycles mediated by diboronic acid with water as the hydrogen atom source is reported. A variety of N-heterocycles can be hydrogenated with medium to excellent yields within 10 min. Complete deuterium incorporation from stoichiometric D2O onto substrates further exemplifies the H/D atom sources. Mechanism studies reveal that the reduction proceeds with initial 1,2-addition, in which diboronic acid synergistically activates substrates and water via a six-membered ring transition state.

NOVEL PHENOL DERIVATIVE

Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a novel phenol derivative represented by general formula (1) that is shown in FIG. 1; a pharmaceutically acceptable salt t

1,3,2λ5-Benzothiazaphosphole 2-Oxide and 1,3,2λ5-Benzoxazaphosphole 2-Oxide Derivatives, New and Versatile Phosphorylating Reagents

The synthesis of the highly reactive five-membered cyclic phosphorylating reagents 6a and 12 is decribed.The reagent 6a monophosphorylates alcohols without ring opening, whereas 12 diphosphorylates with ring opening yielding phosphate triesters.