443640-63-9Relevant academic research and scientific papers
Enantioselective synthesis of 2-substituted and 3-substituted piperidines through a bromoaminocyclization process
Zhou, Ling,Tay, Daniel Weiliang,Chen, Jie,Leung, Gulice Yiu Chung,Yeung, Ying-Yeung
supporting information, p. 4412 - 4414 (2013/05/22)
A catalytic enantioselective bromocyclization of olefinic amides using amino-thiocarbamates as the catalysts has been developed. The resulting enantioenriched 2-substituted 3-bromopiperidines can readily be transformed to 3-substituted piperidines through
A highly enantioselective approach towards 2-substituted 3-bromopyrrolidines
Chen, Jie,Zhou, Ling,Yeung, Ying-Yeung
supporting information; experimental part, p. 3808 - 3811 (2012/06/04)
A facile and highly enantioselective approach towards 2-substituted 3-bromopyrrolidines has been developed. The process involves an amino-thiocarbamate catalyzed bromoaminocyclization of 1,2-disubstituted olefinic amides. The pyrrolidine products could re
Manganese(III) acetate mediated oxidative radical cyclizations. Toward vicinal all-carbon quaternary stereocenters
Logan, Angus W.J.,Parker, Jeremy S.,Hallside, Michal S.,Burton, Jonathan W.
, p. 2940 - 2943 (2012/08/28)
Manganese(III) acetate mediated oxidative radical cyclizations have been used to synthesize a range of densely functionalized and sterically congested cyclopentane-lactones. A number of the resulting lactones contain vicinal all-carbon quaternary stereocenters adjacent to a tertiary benzylic stereocenter and are formed with high levels of stereocontrol.
A facile synthesis of aryldihydropyrans using a Sonogashira-selenoetherification strategy
Brimble, Margaret A,Pavia, Gabrielle S,Stevenson, Ralph J
, p. 1735 - 1738 (2007/10/03)
A high yielding and convenient synthesis of 2-aryl-2,5-dihydro-2H-pyrans is reported. Sonogashira coupling of 4-pentyn-1-ol and 5-hexyn-2-ol with a range of phenyl and naphthyl bromides affords the appropriate aryl acetylenic alcohols which then undergo r
