443648-89-3 Usage
Uses
Used in Pharmaceutical Synthesis:
cis-3,4-Piperidinediol hydrochloride is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of a wide range of biologically active molecules, making it a valuable asset in the development of new drugs.
Used in Biotechnology Applications:
In the biotechnology industry, cis-3,4-Piperidinediol hydrochloride is utilized as a building block for the development of biologically active compounds. Its versatility in chemical reactions enables the production of molecules with specific biological functions, which can be applied in various research and therapeutic areas.
Used in Drug Development:
cis-3,4-Piperidinediol hydrochloride is used as a starting material for the development of new drugs. Its chemical properties make it suitable for the creation of molecules with potential therapeutic effects, contributing to the advancement of medical treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 443648-89-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,3,6,4 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 443648-89:
(8*4)+(7*4)+(6*3)+(5*6)+(4*4)+(3*8)+(2*8)+(1*9)=173
173 % 10 = 3
So 443648-89-3 is a valid CAS Registry Number.
443648-89-3Relevant academic research and scientific papers
Synthesis, molecular modeling and evaluation of α-glucosidase inhibition activity of 3,4-dihydroxy piperidines
Kasturi, Siva Prasad,Surarapu, Sujatha,Uppalanchi, Srinivas,Dwivedi, Shubham,Yogeeswari, Perumal,Sigalapalli, Dilep Kumar,Bathini, Nagendra Babu,Ethiraj, Krishna S.,Anireddy, Jaya Shree
, p. 39 - 52 (2018/03/09)
Biological evaluation of 3,4-dihydroxy piperidines as α-glucosidase inhibitors is being reported for the first time. Forty-five derivatives (amides, di-amides and sulfonamides) were made using cis and trans 3,4-dihydroxy piperidines to evaluate their α-glucosidase inhibition activity. Polar groups (-OH, -NH2) on phenyl ring having derivatives 5i, 5l, 7g, 7i & 12j showed excellent activity compared to standard references. Acarbose, Voglibose and Miglitol were used as standard references. Molecular docking simulations were done for compounds to identify important binding modes responsible for inhibition activity of α-glucosidase.
