443648-97-3 Usage
Uses
Used in Pharmaceutical Synthesis:
(3R,4R)-rel-3,4-Piperidinediol Hydrochloride is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique stereochemistry and functional groups make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Biologically Active Compounds Synthesis:
(3R,4R)-rel-3,4-Piperidinediol Hydrochloride is also used as a starting material for the synthesis of biologically active compounds. Its structural features allow for the creation of molecules with specific biological activities, which can be further optimized for various therapeutic purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 443648-97-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,3,6,4 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 443648-97:
(8*4)+(7*4)+(6*3)+(5*6)+(4*4)+(3*8)+(2*9)+(1*7)=173
173 % 10 = 3
So 443648-97-3 is a valid CAS Registry Number.
443648-97-3Relevant academic research and scientific papers
Kasturi, Siva Prasad,Surarapu, Sujatha,Uppalanchi, Srinivas,Dwivedi, Shubham,Yogeeswari, Perumal,Sigalapalli, Dilep Kumar,Bathini, Nagendra Babu,Ethiraj, Krishna S.,Anireddy, Jaya Shree
, p. 39 - 52 (2018)
Biological evaluation of 3,4-dihydroxy piperidines as α-glucosidase inhibitors is being reported for the first time. Forty-five derivatives (amides, di-amides and sulfonamides) were made using cis and trans 3,4-dihydroxy piperidines to evaluate their α-glucosidase inhibition activity. Polar groups (-OH, -NH2) on phenyl ring having derivatives 5i, 5l, 7g, 7i & 12j showed excellent activity compared to standard references. Acarbose, Voglibose and Miglitol were used as standard references. Molecular docking simulations were done for compounds to identify important binding modes responsible for inhibition activity of α-glucosidase.
