443685-65-2Relevant academic research and scientific papers
MAPK INHIBITORS
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, (2016/03/22)
The present invention relates to certain novel substituted thiophene compounds and the finding that they display useful efficacy in the inhibition of the p38α MAPK enzyme. This provides for use of the compounds in various treatment methodologies related to MAPK inhibition, including the treatment of inflammation.
COMPOUNDS SUBSTITUTED WITH BICYCLIC AMINO GROUPS
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Page/Page column 248-249, (2010/11/30)
[Object]The object of the present invention is to provide compounds which are able to inhibit the production of inflammatory cytokines.[Solution]Compounds of the general formula (I) below, or pharmacologically acceptable salts, esters or other derivatives
