443688-50-4Relevant academic research and scientific papers
Novel water soluble 2,6-dimethoxyphenyl ester derivatives with intravenous anaesthetic activity
Bennett, D. Jonathan,Anderson, Alison,Buchanan, Kirsteen,Byford, Alan,Cooke, Andrew,Gemmell, David K.,Hamilton, Niall M.,Maidment, Maurice S.,McPhail, Petula,Stevenson, Donald F. M.,Sundaram, Hardy,Vijn, Peter
, p. 1971 - 1975 (2007/10/03)
A number of water soluble bis-amino-2,6-dimethoxyphenyl ester derivatives were found to exhibit improved anaesthetic activity in mice relative to propofol 1. Of the analogues disclosed, 44 was further profiled in rodents and found to be a superior agent to propofol for the induction and maintenance of anaesthesia.
