443749-31-3

Basic information

• Product Name: N-(1,3-benzothiazol-2-yl)-3-hydroxy-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxamide
• CAS NO: 443749-31-3
• Molecular Formula: C₂₀H₁₅N₃O₃S
• Molecular Weight: 377.4164
• Mol File: 443749-31-3.mol
• Article Data: 1

Chemical Properties

• Density: 1.56g/cm³
• Refractive Index: 1.79
• CAS DataBase Reference: N-(1,3-benzothiazol-2-yl)-3-hydroxy-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,3-benzothiazol-2-yl)-3-hydroxy-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxamide(443749-31-3)
• EPA Substance Registry System: N-(1,3-benzothiazol-2-yl)-3-hydroxy-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxamide(443749-31-3)

Safety Data

• Hazardous Substances Data: 443749-31-3(Hazardous Substances Data)

Upstream product

• 136-95-8 2-amino-benzthiazole 
• 84088-84-6 ethyl 1-hydroxy-3-oxo-6,7-dihydro-3H,5H-pyrido-[3,2,1-ij]quinoline-2-carboxylate 

Relevant articles and documents

4-Hydroxy-2-quinolones 148. Synthesis and antitubercular activity of 1-hydroxy-3-oxo-6,7-dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid N-R-amides

An improved method for the preparation of ethyl 1-hydroxy-3-oxo-6,7- dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate has been proposed and a series of hetarylamides has been synthesized from it. A comparative analysis has been carried out of the antitubercular activities of the synthesized compounds with the active structural analogs 4-hydroxy-2-oxo-1,2-dihydroquinoline-3 and 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]quinoline-2-carboxamides studied before.