443754-46-9Relevant academic research and scientific papers
Copper-Catalyzed Umpolung of Imines through Carbon-to-Nitrogen Boryl Migration
Li, Zhenghua,Zhang, Liang,Nishiura, Masayoshi,Hou, Zhaomin
, p. 4388 - 4393 (2019/05/08)
We report a general strategy for the catalytic umpolung of imines, which was enabled by an unprecedented 1,2-boryl carbon-to-nitrogen migration. Based on the discovery of a rearrangement of an α-borylalkylamido copper intermediate to an α-borylaminoalkyl
Synthesis of substituted γ-lactam via Pd(0)-catalyzed cyclization of alkene-tethered carbamoyl chloride
Chen, Chen,Hu, Jian,Su, Jianhua,Tong, Xiaofeng
supporting information, p. 3229 - 3231 (2014/06/09)
Pd(0)-catalyzed carboiodonation of but-3-enylcarbamic chloride has been developed with NaI as additive, which provides a ready access to substituted γ-lactam bearing an alkyl iodide group. This reaction features alkyl iodide reductive elimination as a key step in catalytic cycle, indicating the crucial role of additive NaI.
Bu4N+ alkoxide-initiated/autocatalytic addition reactions with organotrimethylsilanes
Das, Manas,O'Shea, Donal F.
, p. 5595 - 5607 (2014/07/08)
The use of Me3SiO-/Bu4N+ as a general activator of organotrimethylsilanes for addition reactions has been established. The broad scope of the method offers trimethylsilanes (including acetate, allyl, propargyl, benzyl, dithiane, heteroaryl, and aryl derivatives) as bench-stable organometallics that can be readily utilized as carbanion equivalents for synthesis. Reactions are achieved at rt without the requirement of specialized precautions that are commonplace for other organometallics.
Allyl-, allenyl-, and propargyl-transfer reactions through cleavage of C-C bonds catalyzed by an n-heterocyclic carbene/copper complex: Synthesis of multisubstituted pyrroles
Sai, Masahiro,Yorimitsu, Hideki,Oshima, Koichiro
supporting information; scheme or table, p. 3294 - 3298 (2011/06/21)
Cat. in the bag: The pictured copper complex can promote C-C bond cleavage through retro-allylation of homoallyl alcohols to form allylcopper species. This process is applicable to catalytic allylation of aldehydes and imines with homoallyl alcohols. The method has also been extended to regioselective allenylation and propargylation of imines. Copyright
