443797-72-6Relevant academic research and scientific papers
Total synthesis of (-)-rhazinilam: Asymmetric C-H bond activation via the use of a chiral auxiliary
Johnson, James A.,Li, Ning,Sames, Dalibor
, p. 6900 - 6903 (2007/10/03)
The antitumor agent (-)-rhazinilam was synthesized in three major steps, namely the pyrrole synthesis, selective C-H bond activation, and direct macrolactam formation. The key step involved asymmetric C-H bond functionalization (dehydrogenation) of the di
