443905-53-1 Usage
Uses
Used in Pharmaceutical Industry:
2-(4-Isopropylphenoxy)acetohydrazide is used as a pharmaceutical intermediate for the synthesis of various therapeutic agents. Its antimicrobial and antiviral properties make it a valuable component in the development of new drugs to combat infectious diseases.
Used in Anticancer Applications:
In the field of oncology, 2-(4-Isopropylphenoxy)acetohydrazide is utilized as a potential therapeutic agent for the treatment of various types of cancer. Its mechanism of action may involve targeting specific cellular pathways or processes that contribute to tumor growth and progression.
Used in Neurodegenerative Disorder Treatment:
2-(4-Isopropylphenoxy)acetohydrazide is also being studied for its potential use in treating neurodegenerative disorders. Its role in this context could involve the modulation of cellular processes that lead to neuronal damage or degeneration, offering a new avenue for therapeutic intervention.
Used in Antioxidant Formulations:
Due to its antioxidant properties, 2-(4-Isopropylphenoxy)acetohydrazide is used in the development of food additives and cosmetics. Its ability to neutralize free radicals and protect against oxidative stress makes it a promising ingredient for products aimed at preserving health and promoting longevity.
Used in Cosmetics Industry:
In the cosmetics industry, 2-(4-Isopropylphenoxy)acetohydrazide is used as an ingredient in various formulations to provide antioxidant benefits to the skin. Its inclusion in cosmetic products may help to protect against environmental damage and promote skin health.
Check Digit Verification of cas no
The CAS Registry Mumber 443905-53-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,3,9,0 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 443905-53:
(8*4)+(7*4)+(6*3)+(5*9)+(4*0)+(3*5)+(2*5)+(1*3)=151
151 % 10 = 1
So 443905-53-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H16N2O2/c1-8(2)9-3-5-10(6-4-9)15-7-11(14)13-12/h3-6,8H,7,12H2,1-2H3,(H,13,14)
443905-53-1Relevant articles and documents
Staphylococcus aureus rnpa inhibitors: Computational-guided design, synthesis and initial biological evaluation
Suigo, Lorenzo,Chojnacki, Michaelle,Zanotto, Carlo,Sebastián-Pérez, Victor,Morghen, Carlo De Giuli,Casiraghi, Andrea,Dunman, Paul M.,Valoti, Ermanno,Straniero, Valentina
, (2021)
Antibiotic resistance is spreading worldwide and it has become one of the most important issues in modern medicine. In this context, the bacterial RNA degradation and processing machinery are essential processes for bacterial viability that may be exploited for antimicrobial therapy. In Staphylococcus aureus, RnpA has been hypothesized to be one of the main players in these mech-anisms. S. aureus RnpA is able to modulate mRNA degradation and complex with a ribozyme (rnpB), facilitating ptRNA maturation. Corresponding small molecule screening campaigns have recently identified a few classes of RnpA inhibitors, and their structure activity relationship (SAR) has only been partially explored. Accordingly, in the present work, using computational modeling of S. aureus RnpA we identified putative crucial interactions of known RnpA inhibitors, and we used this information to design, synthesize, and biologically assess new potential RnpA inhibitors. The present results may be beneficial for the overall knowledge about RnpA inhibitors belonging to both RNPA2000-like thiosemicarbazides and JC-like piperidine carboxamides molecular classes. We evaluated the importance of the different key moieties, such as the dichlorophenyl and the piperidine of JC2, and the semithiocarbazide, the furan, and the i-propylphenyl ring of RNPA2000. Our efforts could provide a foundation for further computational-guided investigations.
