443914-96-3Relevant academic research and scientific papers
ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS
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Paragraph 0212-0213; 0227-0228, (2021/02/05)
The present invention provides novel compounds which activate the Kv7 potassium channels. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders responsive to the activation of Kv7 potassium channels.
Diaminothiazoles having antiproliferative activity
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, (2008/06/13)
Disclosed are novel diaminothiazoles that are selective inhibitors of Cdk4. These compounds and their pharmaceutically acceptable salts and esters are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds as well as intermediates useful in the preparation of the compounds.
