443986-79-6Relevant academic research and scientific papers
Respiratory syncytial virus fusion inhibitors. Part 7: Structure-activity relationships associated with a series of isatin oximes that demonstrate antiviral activity in vivo
Sin, Ny,Venables, Brian L.,Combrink, Keith D.,Gulgeze, H. Belgin,Yu, Kuo-Long,Civiello, Rita L.,Thuring, Jan,Wang, X. Alan,Yang, Zheng,Zadjura, Lisa,Marino, Anthony,Kadow, Kathleen F.,Cianci, Christopher W.,Clarke, Junius,Genovesi, Eugene V.,Medina, Ivette,Lamb, Lucinda,Krystal, Mark,Meanwell, Nicholas A.
scheme or table, p. 4857 - 4862 (2010/04/29)
A series of bezimidazole-isatin oximes were prepared and profiled as inhibitors of respiratory syncytial virus (RSV) replication in cell culture. Structure-activity relationship studies were directed toward optimization of antiviral activity, cell permeab
