444002-83-9

Upstream product

• 675-20-7 piperidin-2-one 
• 875238-74-7 2-bromo-4-nitro-1-(trifluoromethyl)benzene 
• 367-67-9 2-bromo-5-nitro-benzotrifluoride 

Downstream Products

• 444002-84-0 1-(4-amino-2-trifluoromethyl-phenyl)-piperidin-2-one 

Relevant academic research and scientific papers

PROLINE DERIVATIVES

The invention relates to novel compounds of formula (I), wherein X, Y, R1, R2, R3, R4 and n have the meaning cited in claim 1, are inhibitors of the coagulation factor Xa and can be used for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.

CARBONYL COMPOUNDS

The invention relates to the novel compounds of formula (I), wherein D, E, G, W, X, Y, T, R and R are defined as in claim 1. The inventive compounds inhibit coagulation factor Xa and can be used in the prophylaxis and/or therapy of thrombo-embolic diseases and for treating tumors.

Phenyl derivatives

Novel compounds of the formula I in which W, X, Y, T, R1 and R2 are as defined in Patent claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders.