4442-90-4

Basic information

• Product Name: 2-cyclohexylideneethanamine
• CAS NO: 4442-90-4
• Molecular Formula: C₈H₁₅N
• Molecular Weight: 125.214
• Mol File: 4442-90-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 211.6°Cat760mmHg
• Flash Point: 88°C
• Density: 0.983g/cm³
• CAS DataBase Reference: 2-cyclohexylideneethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclohexylideneethanamine(4442-90-4)
• EPA Substance Registry System: 2-cyclohexylideneethanamine(4442-90-4)

Safety Data

• Hazardous Substances Data: 4442-90-4(Hazardous Substances Data)

Upstream product

• 4435-18-1 2-cyclohexylideneacetonitrile 
• 108-94-1 cyclohexanone 
• 138313-56-1 N-(2-Cyclohexylidenethyl)phthalimid 
• 6318-49-6 1-vinylcyclohexyl acetate 

Downstream Products

• 138313-52-7 N-(2-Cyclohexylidenethyl)formamid 
• 59874-98-5 2,2,2-trichloro-N-(2-cyclohexylideneethyl)acetamide 
• 1599461-71-8 (Z)-ethyl 3-((2-cyclohexylideneethyl)amino)-3-phenylacrylate 
• 138313-50-5 2-Cyclohexylidenethylisocyanid 
• 138313-51-6 2-Cyclohexylidenethylcyanid 

Relevant articles and documents

Amination of Carbenium Ions Generated by Directed Protonolysis of Cyclopropane

Directed intramolecular protonolyis of the cyclopropane C-C bond is demonstrated as a strategy to generate carbenium ions. This intermediate can be subjected to amination with nitriles under Ritter reaction conditions. Directing groups such as carbamate, carboxamide, urea, ester, and ketone were found to be efficient for regioselective anti-Markovnikov cleavage of cyclopropane. Depending on the directing group, the amination provided orthogonally protected 1,4-diamine, ?-amino carboxylic, and ?-amino ketone derivatives.

New Syntheses of Isomerically Pure Allyl and Propargyl Cyanides by Isocyanide-Cyanide Rearrangement

A new route for the synthesis of isomerically pure allyl and propargyl cyanides has been developed.Allylic amines are synthesized from the corresponding alcohols by Mitsunobu or by Overman reaction.Formylation with formic acid derivatives provides N-substituted formamides, which are dehydrated to isocyanides. 1,2-Sigmatropic rearrangement by flash pyrolysis provides the isomerically pure allyl and propargyl cyanides. Key Words: Isocyanide-cyanide rearrangment / Cyanides, allyl- and propargyl-

PALLADIUM(0) CATALYZED AZIDATION AND AMINATION OF ALLYL ACETATES. SELECTIVE SYNTHESIS OF ALLYL AZIDES AND PRIMARY ALLYLAMINES

Palladium catalyzed reaction of allyl acetates with azide ion gives allyl azides, which are readily converted into the corresponding primary allylamines upon treatment with PPh3/NaOH.