444575-98-8 Usage
Uses
Used in Pharmaceutical Research:
Shu-9119 is used as a research compound for investigating the role of melanocortin-4 receptor (MC4R) in the regulation of food intake and energy balance. Its application aids in understanding the molecular mechanisms of energy homeostasis and the development of potential therapeutic targets for metabolic disorders.
Used in Obesity Treatment Research:
Shu-9119 is used as a potential therapeutic agent for obesity and related metabolic disorders. By acting as a selective antagonist of the MC4R, it may help modulate feeding behavior and energy expenditure, offering a potential treatment approach for obesity.
Used in Central Nervous System Research:
Shu-9119 is used as a tool in studying the physiological and behavioral effects of melanocortin signaling in the central nervous system. This application provides insights into the broader implications of MC4R dysfunction on neurological health and behavior.
Used in Drug Development:
Shu-9119 is used in the development of new drugs targeting the melanocortin-4 receptor (MC4R) pathway. Its antagonistic properties make it a valuable compound for designing drugs that could potentially treat obesity and other metabolic disorders by modulating the MC4R pathway.
Check Digit Verification of cas no
The CAS Registry Mumber 444575-98-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,4,5,7 and 5 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 444575-98:
(8*4)+(7*4)+(6*4)+(5*5)+(4*7)+(3*5)+(2*9)+(1*8)=178
178 % 10 = 8
So 444575-98-8 is a valid CAS Registry Number.
444575-98-8Relevant academic research and scientific papers
Asymmetric catalysis on the intramolecular cyclopropanation of α-Diazo-β-keto sulfones
Honma, Masahiro,Sawada, Takashi,Fujisawa, Yuri,Utsugi, Masayuki,Watanabe, Hideaki,Umino, Akinori,Matsumura, Takehiko,Hagihara, Takayuki,Takano, Masashi,Nakada, Masahisa
, p. 2860 - 2861 (2007/10/03)
This work describes the development of a highly enantioselective asymmetric catalysis on the intramolecular cyclopropanation of α-diazo-β-keto sulfones. We have found that the catalytic asymmetric intramolecular reactions of α-diazo-β-keto sulfones generally proceed with high enantioselectivity when the α-diazo-β-keto mesityl sulfone is used with the newly prepared ligand 2e. The absolute configuration of products has been determined by X-ray crystallographic analysis, and the outcome of the enantioselectivities is explained well by our proposed models A and B. The products possess great potential for natural product synthesis because (1) many different chemistries of cyclopropane, ketone, and sulfone are available, and (2) the products are generally highly crystalline, facilitating the supplies of enantiomerically pure synthetic intermediates. Copyright
