444597-03-9Relevant academic research and scientific papers
Inhibitors of the NAD+-dependent protein desuccinylase and demalonylase sirt5
Maurer, Benjamin,Rumpf, Tobias,Scharfe, Michael,Stolfa, Diana A.,Schmitt, Martin L.,He, Wenjuan,Verdin, Eric,Sippl, Wolfgang,Jung, Manfred
, p. 1050 - 1053 (2012)
NAD+-dependent histone deacetylases (sirtuins) play important roles in epigenetic regulation but also through nonhistone substrates for other key cellular events and have been linked to the pathogenesis of cancer, neurodegeneration, and metabol
