444753-75-7

Upstream product

• 444753-72-4 2-(2-(benzyloxy)ethyl)-3-hydroxycyclohex-2-en-1-one 
• 54555-84-9 benzyl iodoethyl ether 
• 444753-73-5 (S)-2-[2-(2-Benzyloxy-ethyl)-3-oxo-cyclohex-1-enylamino]-3-methyl-butyric acid benzyl ester 

Downstream Products

• 444753-76-8 N-methyl-N-[3-hydroxy-2-(2`-hydroxyethyl)]phenyl-(S)-valine 
• 444753-81-5 (S)-2-({3-Benzyloxy-2-[(S)-2-((R)-2-hydroxy-1-phenyl-ethylamino)-2-methoxycarbonyl-ethyl]-phenyl}-methyl-amino)-3-methyl-butyric acid benzyl ester 
• 444753-79-1 (S)-2-({3-Benzyloxy-2-[(S)-2-cyano-2-((R)-2-hydroxy-1-phenyl-ethylamino)-ethyl]-phenyl}-methyl-amino)-3-methyl-butyric acid benzyl ester 
• 444753-83-7 N-methyl-N-[3-benzoxy-2-[(S)-2`-(tert-butyloxycarbonyl)amino-2`-methoxycarbonyl]ethyl]phenyl-(S)-valine benzyl ester 

Relevant academic research and scientific papers

Synthesis of 7-substituted benzolactam-V8s and their selectivity for protein kinase C isozymes.

[reaction: see text] Condensation of L-valine benzyl ester toluenesulfonic acid salt with a substituted cyclohexadione followed by aromatization with the assistance of NBS provides an N-aryl L-valine benzyl ester. This intermediate is converted into 7-sub