444771-86-2Relevant academic research and scientific papers
New heterocyclic hybrids of pyrazole and its bioisosteres: Design, synthesis and biological evaluation as dual acting antimalarial-antileishmanial agents
Bekhit, Adnan A.,Hassan, Ahmed M.M.,Abd El Razik, Heba A.,El-Miligy, Mostafa M.M.,El-Agroudy, Eman J.,Bekhit, Alaa El-Din A.
, p. 30 - 44 (2015)
A new series of pyrazole derivatives were synthesized by hybridization with five-membered heterocyclic moieties such as thiazoles, thiazolidinones, 1,3,4-thiadiazoles and pyrazolines. The compounds were evaluated for their in vivo antimalarial activity ag
INHIBITORS OF HEPATITIS C VIRUS REPLICATION
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Paragraph 0660-0661, (2019/05/15)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
INHIBITORS OF HEPATITIS C VIRUS REPLICATION
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Page/Page column 95, (2010/11/04)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
