444885-19-2

Upstream product

• 444885-16-9 (6Z,9S)-1-(benzyloxy)-9-(tert-butyldimethylsilyloxy)-9-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]non-6-en-2-yn-4-ol 
• 4039-82-1 Benzyl propargyl ether 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 149859-05-2 1-[2',2'-dimethyl-(4'R)-1',3'-dioxolan-4'-yl]-(1S)-3-butyn-1-ol 
• 444885-23-8 1,2,3-trideoxy-4-O-(tert-butyldimethylsilyl)-5,6-O-isopropylidene-D-erythro-hex-1-ynitol 
• 444885-14-7 tert-butyl{(1S)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]hept-6-en-3-ynyloxy}dimethylsilane 
• 444885-15-8 (2RS,7S)-7-(tert-butyldimethyl-silanyloxy)-7-[(4R)-2,2-dimethyl-1,3-dioxalan-4-yl]-4-heptene-1,2-diol 
• 444885-24-9 (S)-7-(tert-Butyl-dimethyl-silanyloxy)-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hept-4-yne-1,2-diol 

Downstream Products

• 444885-20-5 methyl (2E,4S,6Z)-12-(benzyloxy)-4-(tert-butyldimethylsilyloxy)-9-hydroxydodeca-2,6-dien-10-ynoate 
• 1026619-19-1 (2E,6Z)-(S)-12-Benzyloxy-4,9-dihydroxy-dodeca-2,6-dien-10-ynoic acid methyl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of syn-2,7-disubstituted-4,5-oxepenes

An efficient synthesis of the title compounds as pure enantiomers is reported. The method is based on the intramolecular trapping of a carbocation generated by acid treatment of exo-Co2(CO)6-propargyl alcohols by a stereochemically c