4449-55-2 Usage
Uses
Used in Pharmaceutical Industry:
Warangalone is used as an anti-malarial agent for its ability to inhibit the growth of both chloroquine-sensitive (3D7) and chloroquine-resistant (K1) strains of the malaria parasite. This makes it a promising candidate for the development of new treatments against drug-resistant malaria.
Used in Research and Development:
Warangalone is used as a research compound for studying the mechanisms of action against malaria parasites and the inhibition of cyclic AMP-dependent protein kinase catalytic subunit (cAK). This can lead to the discovery of new therapeutic targets and the development of novel drugs for various diseases.
Used in Drug Discovery:
Warangalone's potent anti-malarial activity and cAK inhibition make it a valuable compound for drug discovery efforts. It can be used as a starting point for the development of new drugs targeting malaria and other diseases where cAK plays a significant role.
Check Digit Verification of cas no
The CAS Registry Mumber 4449-55-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,4 and 9 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4449-55:
(6*4)+(5*4)+(4*4)+(3*9)+(2*5)+(1*5)=102
102 % 10 = 2
So 4449-55-2 is a valid CAS Registry Number.
InChI:InChI=1/C25H24O5/c1-14(2)5-10-18-23-17(11-12-25(3,4)30-23)21(27)20-22(28)19(13-29-24(18)20)15-6-8-16(26)9-7-15/h5-9,11-13,26-27H,10H2,1-4H3
4449-55-2Relevant academic research and scientific papers
Preparation method of isoflavone compounds
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Paragraph 0049; 0051; 0062; 0063, (2019/10/10)
The invention belongs to the technical field of medicine, and particularly discloses a preparation method of isoflavone compounds. The structures of the compounds are shown in the formula I and the formula II. According to the preparation method, genistei
NEW PRENYLATED ISOFLAVONES AND A PRENYLATED DIHYDROFLAVONOL FROM MILLETTIA PACHYCARPA
Singhal, Ashok K.,Sharma, Ram P.,Thyagarajan, Gopalakrishna,Herz, Werner,Govindan, Serengolam V.
, p. 929 - 934 (2007/10/02)
Extraction of Millettia pachycarpa Benth. gave 5,7,4'-trihydroxy-6,8-diprenylisoflavone (1a), 5,7,4'-trihydroxy-6,3'-diprenylisoflavone (2a), 5,7,3',4'-tetrahydroxy-6,8-diprenylisoflavone (3a) and (2R,3R)-5,4'-dihydroxy-8-prenyl-6'',6''-dimethylpyrano-dihydroflavonol (4a) whose structures were established by chemical transformations and spectroscopic means.Pectolinarigenin and salvigenin were isolated from Buddleia macrostachya Benth. - Key Word Index: Millettia pachycarpa; Leguminosae; Lotodoideae; prenylated isoflavones; prenylated dihydroflavonols; Buddleia macrostachya; Buddleiaceae; pectolinarigenin; salvigenin.
