444902-06-1Relevant academic research and scientific papers
Modular synthesis of 1,2-Diamine derivatives by palladium-Catalyzed aerobic oxidative cyclization of allylic sulfamides
McDonald, Richard I.,Stahl, Shannon S.
supporting information; experimental part, p. 5529 - 5532 (2010/09/05)
Chemical equation presented Allylic sulfamides undergo aerobic oxidative cyclization at room temperature, mediated by a Pd(O 2CCF3)2/DMSO catalyst system in tetrahydrofuran. The cyclic sulfamide products are readily converted into 1,2-diamines, and substrates derived from chiral allylic amines cyclize with very high diastereoselectivity.
Asymmetric allylic substitution catalyzed by palladium-Yliphos complex
Ohta, Tetsuo,Sasayama, Hiroyuki,Nakajima, Osakazu,Kurahashi, Nobukazu,Fujii, Takeshi,Furukawa, Isao
, p. 537 - 542 (2007/10/03)
Allylic substitution reactions catalyzed by Pd- or Pt-Yliphos complexes are examined. The reaction of 1,3-diphenyl-2-propenyl acetate with benzylamine proceeded in the presence of Pd(dba)2-Yliphos to give N-benzyl-1,3-diphenyl-2-propenylamine i
The [2,3] sigmatropic rearrangement of N-benzyl-O-allylhydroxylamines
Davies, Stephen G.,Fox, John F.,Jones, Simon,Price, Anne J.,Sanz, Miguel A.,Sellers, Thomas G. R.,Smith, Andrew D.,Teixeira, Fatima C.
, p. 1757 - 1765 (2007/10/03)
The rearrangement of a range of N-benzyl-O-allylhydroxylamines to the corresponding N-allylhydroxylamines upon treatment with n-BuLi in THF, followed by reduction to the corresponding N-allylamines, is described. Mechanistic studies of the transformation are consistent with an intramolecular [2,3] sigmatropic rearrangement.
Facile synthesis of proline based phosphine-oxazoline ligands by formation of a P-N bond
Xu, Guopin,Gilbertson, Scott R
, p. 2811 - 2814 (2007/10/03)
A series of new P-N ligands in which the phosphorus moiety is introduced by formation of a phosphorus-heteroatom bond are synthesized. These ligands are based on proline with chiral centers from both proline and an oxazoline. The two chiral centers are re
N-Benzyltriflamide: a Generally Useful Mitsunobu Reagent for Amine Synthesis
Kathryn, E. Bell,Knight, David W.,Gravestock, Michael B.
, p. 8681 - 8684 (2007/10/02)
N-Benzyl triflamide has been found to be generally useful as a Mitsunobu nucleophile for the preparation of a range of primary and secondary benzylamines from the corresponding alcohols, using the standard reagents DEAD and triphenylphosphine.
