444904-08-9

Upstream product

• 444904-25-0 Benzoic acid (1R,4S,5R)-5-(3-isopropoxy-phenyl)-2,4-dimethyl-2-aza-bicyclo[3.3.1]non-7-yl ester 
• 444904-04-5 (-)-(1R,4S,5S)-5-[3-(1-methylethoxy)phenyl]-2,4-dimethyl-2-azabicyclo[3.3.1]nonan-7-one 
• 444904-06-7 (-)-(1R,4S,5S)-5-[3-(1-methylethoxy)phenyl]-2,4-dimethyl-2-azabicyclo[3.3.1]nonan-7-ol 
• 444904-02-3 (S)-1,2,3,6-tetrahydro-1,3-dimethyl-4-[3-(1-methylethoxy)phenyl]pyridine 

Downstream Products

• 444904-14-7 (-)-(1R,4S,5S)-5-[3-(1-methylethoxy)phenyl]-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]nonan-7-one oxime 
• 444904-17-0 (-)-(1R,4S,5S,7R)-5-[3-(1-methylethoxy)phenyl]-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]nonan-7-amine 
• 444904-20-5 (1R,4S,5S,7R)-(-)-5-(3-hydroxyphenyl)-4-methyl-2-(3-phenylpropyl)-2-azabicylo-[3.3.1]nonan-7-amine 
• 444904-11-4 (1R,4S,5R)-5-(3-Isopropoxy-phenyl)-4-methyl-2-(3-phenyl-propyl)-2-aza-bicyclo[3.3.1]nonan-7-one 
• 444904-09-0 (-)-(1R,4S,5S)-5-[3-(1-methylethoxy)phenyl]-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]nonan-7-ol 

Relevant academic research and scientific papers

Discovery of an opioid κ receptor selective pure antagonist from a library of N-substituted 4β-methyl-5-(3-hydroxyphenyl)morphans

A library of compounds biased toward opioid receptor antagonist activity was prepared by incorporating N-phenylpropyl-4β-methyl-5-(3-hydroxyphenyl)morphans as the core scaffold using simultaneous solution phase synthetic methodology. From this library, N-