444926-58-3Relevant articles and documents
Synthesis of (-)-calicoferol B
Taber, Douglass F.,Jiang, Qin,Chen, Bei,Zhang, Wei,Campbell, Carlton L.
, p. 4821 - 4827 (2007/10/03)
The first total synthesis of (-)-calicoferol B (III) is described. The cyclozirconation product I, prepared in enantiomerically pure form, was converted into the CD ring chiron II. This was coupled with the aromatic A-ring, and then the side chain was constructed with control of relative and absolute configuration to complete the total synthesis of III. The first total synthesis of (-)-calicoferol B (1) is described. The cyclozirconation product 8, prepared in enantiomerically pure form, was converted into the CD ring chiron 6. This was coupled with the aromatic A-ring, and then the side chain was constructed with control of relative and absolute configuration to complete the total synthesis of 1.