444992-85-2

Upstream product

• 444992-83-0 1-methoxy-2,3-bis(methoxymethoxy)-4-((3,4,5-trimethoxyphenyl)-ethynyl)benzene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 290347-62-5 1-bromo-4-methoxy-2,3-bis(methoxymethoxy)-benzene 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 61559-82-8 1-Bromo-2,3dihydroxy-4methoxy-benzene 
• 53560-33-1 3,4,5-trimethoxyphenylacetylene 

Downstream Products

• 109971-63-3 (Z)-3-methoxy-6-(3,4,5-trimethoxystyryl)benzene-1,2-diol 

Relevant academic research and scientific papers

Direct biooxidation of arenes to corresponding catechols with E. coli JM109 (pDTG602). Application to synthesis of combretastatins A-1 and B-1

Convergent syntheses of combretastatins A-1 and B-1 were accomplished via coupling of biocatalytically generated p-bromomethoxycatechol with trimethoxyphenylacetylene.