4452-17-9

Basic information

• Product Name: 2-Propenoic acid, 2-(benzoylamino)-
• CAS NO: 4452-17-9
• Molecular Formula: C10H9NO3
• Molecular Weight: 191.186
• Mol File: 4452-17-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-(benzoylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-(benzoylamino)-(4452-17-9)
• EPA Substance Registry System: 2-Propenoic acid, 2-(benzoylamino)-(4452-17-9)

Safety Data

• Hazardous Substances Data: 4452-17-9(Hazardous Substances Data)

Usage

General Description

2-Propenoic acid, 2-(benzoylamino)-, also known as benzoyl-L-glutamic acid, is a chemical compound classified as an amino acid derivative. It has a molecular formula of C15H13NO4 and a molecular weight of 271.27 g/mol. 2-Propenoic acid, 2-(benzoylamino)- is commonly used in the pharmaceutical industry as a key ingredient in the synthesis of various drugs and pharmaceutical products. It is also utilized in the production of polymers and plastic additives. Additionally, 2-Propenoic acid, 2-(benzoylamino)- has potential applications in the field of organic chemistry and biochemistry for research purposes.

Upstream product

• 17966-68-6 N-benzoylaspartic acid 
• 495-69-2 Hippuric Acid 
• 7664-93-9 sulfuric acid 
• 90839-58-0 2-benzoylamino-3-ethoxy-3-oxo-propanol benzoate 
• 64562-96-5 C₁₁H₁₂ClNO₃ 
• 7244-67-9 methyl N-benzoylalaninate 
• 24153-31-9 2-benzoylaminoacrylic acid methyl ester 
• 55-21-0 benzamide 
• 127-17-3 2-oxo-propionic acid 

Downstream Products

• 109728-15-6 (+/-)-6c-benzoylamino-2,2-dimethyl-5-oxo-hexahydro-[1,4]thiazepine-3r-carboxylic acid methyl ester 
• 33556-39-7 2-benzoylamino-2-mercapto-propionic acid 
• 17966-60-8 D-N-benzoylalanine 
• 2198-64-3 N-benzoyl-L-alanine 
• 24153-31-9 2-benzoylaminoacrylic acid methyl ester 
• 872824-95-8 4-acetoxy-4-chloromethyl-2-phenyl-4H-oxazol-5-one 
• 98947-05-8 2-benzoylamino-2,3-dibromo-propionic acid 
• 99184-20-0 2-benzoylamino-2,3-dichloro-propionic acid 
• 39741-34-9 N-benzoyl-3-chloro-alanine 
• 860175-37-7 6-benzoylamino-2,2-dimethyl-5-oxo-2,3,4,5-tetrahydro-[1,4]thiazepine-3-carboxylic acid methyl ester 
• 111317-85-2 2-Benzoylamino-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester 
• 2198-64-3 N-Benzoylalanine 

Relevant articles and documents

Synthesizing method using serine to prepare Ramipril key intermediate

The invention relates to a synthesizing method using serine to prepare a Ramipril key intermediate. The Ramipril key intermediate is 2-azabicyclo[3.3.0] octane-3-carboxylic acid hydrochloride or benzyl ester hydrochloride. The synthesizing method includes: using the serine as the initial raw material, and sequentially performing esterification, acyl chloride acylation, deacidification, Michael addition, hydrolysis and hydrogenation reduction to obtain the Ramipril key intermediate. The synthesizing method has the advantages that the key intermediate is synthesized by a five-step method, and the synthesizing method is cheap in raw material, environmentally friendly, simple in preparation process, simple to operate, mild in reaction condition, short in reaction cycle, convenient in post-treatment, low in equipment requirement, capable of avoiding heavy metal pollution and the use of expensive catalysts, few in three wastes, high in product yield and purity and suitable for industrial production.