445220-96-2Relevant academic research and scientific papers
Diastereoselective enzymatic synthesis of highly substituted 3,4-dihydropyridin-2-ones via domino Knoevenagel condensation-Michael addition-intramolecular cyclization
Liu, Zhi-Qiang,Liu, Bo-Kai,Wu, Qi,Lin, Xian-Fu
, p. 9736 - 9740 (2011)
A direct method to construct 3,4-dihydropyridin-2-ones by enzymatic condensation of aldehyde with cyanoacetamide and 1,3-dicarbonyl compounds was developed. One ring and four new bonds (two C-C, one C-N, one CC) were formed in one pot. And reaction condit
Synthesis of 3,4-dihydropyridin-2-one derivatives in convergent mode applying bio catalyst vitamin B1 and polymer supported catalyst PEG-SO3H from two different sets of building blocks
Pradhan, Koyel,Bhattacharyya, Pranabes,Paul, Sanjay,Das, Asish R.
, p. 5840 - 5844,5 (2020/08/20)
Two highly efficient, green protocols have been developed for the synthesis of 3,4-dihydropyridin-2-one derivatives from different starting materials exploring two reaction specific catalysts, vitamin B1 (VB 1), and PEG-SO3/sub
Imidazole-catalyzed three-component cascade reaction for the facile synthesis of highly substituted 3,4-dihydropyridin-2-one derivatives
Liu, Zhiqiang,Tan, Lu,Wu, Qi,Lin, Xianfu
, p. 2343 - 2348,6 (2012/12/12)
A novel one-pot protocol for the synthesis of valuable 3,4-dihydropyridin- 2-ones from the condensation of aldehyde with cyanoacetamide and 1,3-dicarbonyl compounds in the presence of imidazole was developed. A series of aldehydes and 1,3-dicarbonyl compounds were employed to examine the scope of substrates for this protocol. This reaction proceeded through the formation of one ring and four new bonds (two Ci￡C, one Ci￡N, one Ci￡C) via the sequence involving Knoevenagel condensation, Michael addition and intramolecular cyclization with moderate to excellent yields. All new compounds were characterized by IR, 1H NMR, 13C NMR and HRMS. Copyright
Nano crystalline ZnO catalyzed one pot multicomponent reaction for an easy access of fully decorated 4H-pyran scaffolds and its rearrangement to 2-pyridone nucleus in aqueous media
Bhattacharyya, Pranabes,Pradhan, Koyel,Paul, Sanjay,Das, Asish R.
supporting information; experimental part, p. 4687 - 4691 (2012/09/05)
A green and highly efficient protocol has been developed for the synthesis of 4H-pyran scaffolds installing a one-pot three-component coupling reaction of an aldehyde, malononitrile, and a 1,3-diketo compound using nano structured ZnO as the catalyst in a
