445266-27-3

Basic information

• Product Name: 2-{[3-cyano-4-(4-fluorophenyl)-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide
• Synonyms: 2-{[3-cyano-4-(4-fluorophenyl)-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide
• CAS NO: 445266-27-3
• Molecular Formula: C21H18FN3OS2
• Molecular Weight: 411.5155232
• Mol File: 445266-27-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-{[3-cyano-4-(4-fluorophenyl)-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[3-cyano-4-(4-fluorophenyl)-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide(445266-27-3)
• EPA Substance Registry System: 2-{[3-cyano-4-(4-fluorophenyl)-6-(2-thienyl)-2-pyridinyl]sulfanyl}-N-isopropylacetamide(445266-27-3)

Safety Data

• Hazardous Substances Data: 445266-27-3(Hazardous Substances Data)

Upstream product

• 7357-70-2 Cyanothioacetamide 
• 75726-96-4 2-bromo-N-isopropylacetamide 
• 366-81-4 1-(4-fluorophenyl)-3-(2-thienyl)-2-propen-1-one 

Relevant articles and documents

ANTIBACTERIAL FAB I INHIBITORS

Disclosed herein are antibacterial compounds that inhibit fabl, a NADH-dependent enoyl [acyl carrier protein] reductase enzyme in the fatty acid biosynthesis pathway. The compounds are represented by structural formulas Ia and Ib: R1 and R2 are independently monocyclic aryl or heteroaryl groups, wherein the groups represented by R1 and R2 are optionally substituted with one or more acyclic substituents; R3 is -H or an optionally substituted C1-C8 aliphatic, C3-C8 cycloaliphatic, aryl, or heteroaryl group. X1 is a bond or a C1-C3 alkylene chain that is optionally substituted with a C1-C4 alkyl or an acidic group. X2 is an aryl, heteroaryl or C3-C8 cycloaliphatic ring, wherein the group represented by X2 is optionally substituted with triazole, tetrazole, and/or one or more acyclic substituents.