445291-68-9

Upstream product

• 106-49-0 p-toluidine 
• 445291-56-5 2-(N-methyl-N-phenyl)aminochromone-3-carboxaldehyde 
• 99-99-0 1-methyl-4-nitrobenzene 
• 17422-74-1 3-Formylchromone 
• 151112-74-2 C₁₇H₁₃NO₃ 
• 213273-03-1 4-oxo-2-(N-phenyl)amino-4H-chromene-3-carbaldehyde 

Downstream Products

• 1246677-42-8 [N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde 
• 1268279-39-5 N-(4-methylphenyl)-4-oxo-4H-1-benzopyran-3-carboxamide 
• 1293279-25-0 6,8-di[N-(4-methylphenyl)imino]-7H-pyrano[3,2-c:5,6-c']dicoumarin 
• 1293279-22-7 C₃₃H₂₆N₂O₄ 
• 1345096-82-3 C₁₈H₁₅NO₃ 
• 1345096-71-0 C₁₈H₁₅NO₃ 
• 58272-99-4 (E/Z)-3-((p-tolylamino)methylene)chromane-2,4-dione 
• 1535170-93-4 4-chloro-3-dichloromethyl-2-N-(p-tolyl)imino-2H-1-benzopyran 

Relevant academic research and scientific papers

Regio- and stereoselective synthesis of 1-benzopyrano[2,3-b]pyrrolo[2,3-d] pyridines: A microwave-accelerated intramolecular [3+2] cycloaddition reaction of azomethine ylide

Figure represented. Regio- and stereoselective syntheses of tetracyclic compounds having chromone, pyrrolidine, and piperidine rings have been accomplished by an intramolecular [3+2] cycloaddition reaction involving azomethine ylide. The reactions were ca

A one-pot rearrangement of 2-(N-Alkyl-N-aryl)aminochromone-3-carbaldehyde to N-Alkyl-3-salicyloyl-2-quinolone - An antileishmanial agent

2-(N-Aryl)aminochromone-3-carbaldehyde does not show any change on heating in acetic acid, but under the same reaction conditions 2-(N-alkyl-N-aryl) aminochromone-3-carbaldehyde rearranges to 3-salicyloyl-2-quinolones, which exhibits antileishmanial activ

Rearrangements of N-alkyl-/aryl-nitrones derived from 4-oxo-4H-1- benzopyran-3-carboxaldehyde - A solvent-dependent process

C-(4-Oxo-4H-1-benzopyran-3-yl)-N-alkyl-/aryl-nitrones derived from 4-oxo-4H-1-benzopyran-3-carboxaldehyde, rearrange to 2-alkyl-/aryl-amino-3- formylchromone and/or 3-(alkyl-/aryl-aminomethylene)chroman-2,4-dione depending upon the reaction medium. 3-(Alkylaminomethylene)chroman-2,4-dione has been utilized in the synthesis of 1-benzopyrano[3,4-d]isoxazole-4-one.

One-pot Synthesis of 2-alkyl/arylamino-4-oxo-4H-1-benzopyran-3-carboxaldehyde from 4-oxo-4H-1-benzopyran-3-carboxaldehyde

Zn/NH4Cl - Mediated reactions of aldehyde 1 with nitro compounds 2 afford 2-(N-alkyl/arylamino)-3-formylchromones 4, which on heating with 70 percent H2SO4 produces 9a-d and 11e-h from 4a-d and 4e-h, respectively.

A versatile route to 2-alkyl-/aryl-amino-3-formyl- and hetero-annelated-chromones, through a facile nucleophilic substitution at C2 in 2-(N-methylanilino)-3-formylchromones

The N-methylanilino group in 2-(N-methylanilino)-3-formylchromones, obtained in high yield by rearrangement of C(4-oxo-4H[1]-benzopyran-3-yl)-N-phenylnitrones to 2-anilino-3-formyl-chromones followed by N-methylation, undergoes facile nucleophilic substitution by a variety of nitrogen nucleophiles, thereby paving the way for synthesis of a variety of novel 2-substituted-3-formylchromone derivatives as well as hetero-annelated chromones.